ID H3KGG3_9BURK Unreviewed; 521 AA.
AC H3KGG3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC {ECO:0000313|EMBL:EHY30793.1};
GN ORFNames=HMPREF9440_01843 {ECO:0000313|EMBL:EHY30793.1};
OS Sutterella parvirubra YIT 11816.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=762967 {ECO:0000313|EMBL:EHY30793.1, ECO:0000313|Proteomes:UP000004956};
RN [1] {ECO:0000313|EMBL:EHY30793.1, ECO:0000313|Proteomes:UP000004956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 11816 {ECO:0000313|EMBL:EHY30793.1,
RC ECO:0000313|Proteomes:UP000004956};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHY30793.1}.
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DR EMBL; AFBQ01000276; EHY30793.1; -; Genomic_DNA.
DR RefSeq; WP_008542980.1; NZ_JH604997.1.
DR AlphaFoldDB; H3KGG3; -.
DR STRING; 762967.HMPREF9440_01843; -.
DR PATRIC; fig|762967.3.peg.1451; -.
DR HOGENOM; CLU_522655_0_0_4; -.
DR OrthoDB; 9786494at2; -.
DR Proteomes; UP000004956; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016645; F:oxidoreductase activity, acting on the CH-NH group of donors; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR017610; tRNA_S-uridine_synth_MnmC_C.
DR NCBIfam; TIGR03197; MnmC_Cterm; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR13847:SF283; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000004956};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 137..493
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 521 AA; 55747 MW; D8B641F6C7E2F416 CRC64;
MTQAVLITPE ASALPEAGAL VDARLAAGAL VRVLAPLDKG APGVEERRVG PGRLQTFRFP
ERELRRECAG GWCEVLLADP ASARSWRAIL TPAARCRFLG TPPAGDPRRD GGVWLPGEDG
AWRVPGDASA PPRIRRAVVV GAGIAGAFTA YELARRGVAV DVIDRWGAPA NGASALRAAI
IHPHWQAADG PTSRLTRQGF GRMLNLLDDF PEAFDPCGVM DVAEDDAEWA KWCRAVEDGR
PFPVPEDFAR LTDRDAARGR TGLPLARGGW WFPKAGVVRP ALLARRLLEA SGARVLMGAE
VRLTREDGLW RARFVRGGAV AAEAEAAVAA SALDACAVLD APADFFGLSP LYGRISLLRD
TDFRDVRCAV TGHGYLVRTE EGFCGVGATY EQGTEPQITA VEAHDRNMEA FSRLLTDTPE
ALWGGYYAGV RAVARDRMPL AGPVTLPAEL EGLTFRGRPE LKDLPVTEGL WGLFGLGSRG
LTWGRILAEH VAAEMTGEPT ILPASLARAV APARFAPVLS R
//
