ID   H3NNL1_9FIRM            Unreviewed;       751 AA.
AC   H3NNL1;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=PASTA domain-containing protein {ECO:0000259|PROSITE:PS51178};
GN   ORFNames=HMPREF9709_00922 {ECO:0000313|EMBL:EHR33986.1};
OS   Helcococcus kunzii ATCC 51366.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Helcococcus.
OX   NCBI_TaxID=883114 {ECO:0000313|EMBL:EHR33986.1, ECO:0000313|Proteomes:UP000004191};
RN   [1] {ECO:0000313|EMBL:EHR33986.1, ECO:0000313|Proteomes:UP000004191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51366 {ECO:0000313|EMBL:EHR33986.1,
RC   ECO:0000313|Proteomes:UP000004191};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Heiman D., Howarth C., Larimer J., Lui A.,
RA   MacDonald P.J.P., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Stolte C.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Helcococcus kunzii ATCC 51366.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHR33986.1}.
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DR   EMBL; AGEI01000021; EHR33986.1; -; Genomic_DNA.
DR   RefSeq; WP_005398366.1; NZ_JH601088.1.
DR   AlphaFoldDB; H3NNL1; -.
DR   STRING; 883114.HMPREF9709_00922; -.
DR   PATRIC; fig|883114.3.peg.912; -.
DR   eggNOG; COG0768; Bacteria.
DR   HOGENOM; CLU_009289_6_0_9; -.
DR   OrthoDB; 9757901at2; -.
DR   Proteomes; UP000004191; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR   CDD; cd06577; PASTA_pknB; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   Pfam; PF03793; PASTA; 2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 2.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004191}.
FT   DOMAIN          690..750
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   751 AA;  85807 MW;  45E8410095CFA41B CRC64;
     MSKKRNKRKM LRTNVKISFS TLLLAFLLLG FIYRLVNLQI VDKYQYKTKG NVAAKVGKVI
     KPERGNILDR NGNPLAISRK IDSLYLLPVI SEEESKKAKE VLRNDVEFEK LDKEKQEELR
     KQASKAIYKN EEIQKIAKIL DIKAEEIYKL IDKGKEGFIY NSLNKSQKSQ IELLNLPYLL
     FMPVDERFYP NNELASNAIG FIEDDVAKYG LEKYYDKFLS GESGYREFYK SVNGTEIPYT
     KTENKNSEDA KNIKSTIDIE LQNILYKHLK DAMITTRSMS ATAVLMNPNN GEVLAMQSFP
     TFDSNKPRDL SSEIDKLFLS NLDDKKQVDY LFRKWENNAV SMEYDPGSVY KVVTTAIALE
     TNSDIKKKIY QDDGFYELAP GVVIKSWRFW DPHGPQNLRE ALKNSSNPVF VQVAKDIGKE
     KYVEYGHTLR LGKKTGIDLP NEINGFFPKD ANISDVDFGT MSYGHYVNVS PIQILSTLNS
     IVNGGRYYKP RVVKEIMDKS NEKVFDISEE YLGNTISETT SKEVKEYLEY TAESYGLNTE
     ELKFGAKTGT TEKYNTHSIF KNESDTIESV FTSIFVTYPS DNPKYTLLVV FDEPLSHTLA
     ADTAKPVAKD IMYDVAEYDL GRPLKNDNNK DLVKIPNLIG KTFEEASKIL DESNILAKTN
     QKIGRYNIIS DQNPKENNLI RANSSISLRF SDNIKVPSMI DMNTETAKKI LELNNVNYKI
     SGEGDKIISQ SIKEGEIINQ NQEIIFYTEE R
//