ID H3ZPX7_THELN Unreviewed; 251 AA.
AC H3ZPX7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=fructose-bisphosphatase {ECO:0000256|ARBA:ARBA00013093};
DE EC=3.1.3.11 {ECO:0000256|ARBA:ARBA00013093};
GN ORFNames=OCC_04927 {ECO:0000313|EMBL:EHR78031.1};
OS Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=523849 {ECO:0000313|EMBL:EHR78031.1, ECO:0000313|Proteomes:UP000015502};
RN [1] {ECO:0000313|EMBL:EHR78031.1, ECO:0000313|Proteomes:UP000015502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51850 / DSM 5473 / JCM 8560 / NS-C
RC {ECO:0000313|Proteomes:UP000015502};
RX PubMed=22493191; DOI=10.1128/JB.00123-12;
RA Gardner A.F., Kumar S., Perler F.B.;
RT "Genome sequence of the model hyperthermophilic archaeon Thermococcus
RT litoralis NS-C.";
RL J. Bacteriol. 194:2375-2376(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-
CC phosphate + phosphate; Xref=Rhea:RHEA:11064, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:32966, ChEBI:CHEBI:43474, ChEBI:CHEBI:57634; EC=3.1.3.11;
CC Evidence={ECO:0000256|ARBA:ARBA00001273};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the inositol monophosphatase superfamily. FBPase
CC class 4 family. {ECO:0000256|ARBA:ARBA00038103}.
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DR EMBL; CP006670; EHR78031.1; -; Genomic_DNA.
DR RefSeq; WP_004069281.1; NC_022084.1.
DR AlphaFoldDB; H3ZPX7; -.
DR STRING; 523849.OCC_04927; -.
DR PaxDb; 523849-OCC_04927; -.
DR GeneID; 16550468; -.
DR KEGG; tlt:OCC_04927; -.
DR HOGENOM; CLU_044118_5_0_2; -.
DR OrthoDB; 58111at2157; -.
DR Proteomes; UP000015502; Chromosome.
DR GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.190.80; -; 1.
DR Gene3D; 3.30.540.10; Fructose-1,6-Bisphosphatase, subunit A, domain 1; 1.
DR InterPro; IPR000760; Inositol_monophosphatase-like.
DR PANTHER; PTHR20854; INOSITOL MONOPHOSPHATASE; 1.
DR PANTHER; PTHR20854:SF4; INOSITOL-1-MONOPHOSPHATASE-RELATED; 1.
DR Pfam; PF00459; Inositol_P; 1.
DR PRINTS; PR00377; IMPHPHTASES.
DR SUPFAM; SSF56655; Carbohydrate phosphatase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277}.
SQ SEQUENCE 251 AA; 28012 MW; 37382B33F56E84C4 CRC64;
MYEWNEIALN LAKDIEREVM PLFGTKKAGE FIGFSPSGDK TKLVDKVAED VVLEYLRPLG
VNVVSEEIGN IEAGSEYTIV VDPIDGSFNF IQGIPIFGFS FAVFKNEKPV YAMIYEFITK
NVYEGIPGEG AYLNGERIRV RHLNEKSISI SFYTRGRGAR LVEKVKRTRV LGAIAVELAY
LARGSLDGVI DIRNYVRPTD IAAGYIIAKE AGAIITDDSG EEIKFRLDAR EKLNIIAVND
KRLLKLILEV I
//
