ID H4GIE9_9LACO Unreviewed; 320 AA.
AC H4GIE9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=LacI family transcriptional regulator LacR {ECO:0000313|EMBL:EHS87370.1};
GN ORFNames=PS3_5138 {ECO:0000313|EMBL:EHS87370.1};
OS Limosilactobacillus gastricus PS3.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1144300 {ECO:0000313|EMBL:EHS87370.1, ECO:0000313|Proteomes:UP000004567};
RN [1] {ECO:0000313|EMBL:EHS87370.1, ECO:0000313|Proteomes:UP000004567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS3 {ECO:0000313|EMBL:EHS87370.1,
RC ECO:0000313|Proteomes:UP000004567};
RX PubMed=23846278;
RA Martin V., Cardenas N., Jimenez E., Maldonado A., Rodriguez J.M.,
RA Fernandez L.;
RT "Genome Sequence of Lactobacillus gastricus PS3, a Strain Isolated from
RT Human Milk.";
RL Genome Announc. 1:E00489-E00413(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHS87370.1}.
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DR EMBL; AICN01000014; EHS87370.1; -; Genomic_DNA.
DR RefSeq; WP_007121833.1; NZ_AICN01000014.1.
DR AlphaFoldDB; H4GIE9; -.
DR STRING; 1144300.PS3_5138; -.
DR PATRIC; fig|1144300.3.peg.345; -.
DR OrthoDB; 43195at2; -.
DR Proteomes; UP000004567; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01544; PBP1_GalR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF151; HTH-TYPE TRANSCRIPTIONAL REPRESSOR MELR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000004567};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..48
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 320 AA; 35229 MW; DFAC9D061490839B CRC64;
MAVTLKNIAD EAGVSLATVS RVLNNDPQLS VSPETRERIV TIAQRLDYNK RRRQSPINRR
LAIVEWYSTE HELSDLYYLN LRLNVERAAQ EAGYSTATVF AGNLTSLADP VDGIVAIGKY
SARQLEKMKR YADVIVDVDG DALAQSIPCV VPDFVGGITQ AVDYLAPQHQ RIGMIAGQET
TGDQETVVDL RLKTFVNLMQ ERKRPDNLTW LGDYSDHSGY EQMQAILQLP VDQRPTAVIV
ANDAMSIGAN RALQEASAAG IKLISFGDVA GVANYIYPPL DAIHVPTDQM AMIGIDLISK
YMNNQLAPER VVVGTQLVTR
//
