ID H5Y1P9_9FIRM Unreviewed; 498 AA.
AC H5Y1P9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:EHQ87802.1};
GN ORFNames=DesyoDRAFT_0622 {ECO:0000313|EMBL:EHQ87802.1};
OS Desulfosporosinus youngiae DSM 17734.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=768710 {ECO:0000313|EMBL:EHQ87802.1, ECO:0000313|Proteomes:UP000005104};
RN [1] {ECO:0000313|EMBL:EHQ87802.1, ECO:0000313|Proteomes:UP000005104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17734 {ECO:0000313|EMBL:EHQ87802.1,
RC ECO:0000313|Proteomes:UP000005104};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Lu M., Land M.L., Hauser L., Pester M.,
RA Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA Woyke T.J.;
RT "The Noncontiguous Finished genome of Desulfosporosinus youngiae DSM
RT 17734.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CM001441; EHQ87802.1; -; Genomic_DNA.
DR RefSeq; WP_007779266.1; NZ_CM001441.1.
DR AlphaFoldDB; H5Y1P9; -.
DR STRING; 768710.DesyoDRAFT_0622; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_4_4_9; -.
DR OrthoDB; 9801659at2; -.
DR Proteomes; UP000005104; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005104}.
FT DOMAIN 8..149
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 186..431
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 498 AA; 56399 MW; 02C0DC69AEE61037 CRC64;
MKILLLEHPR KVCQERCNDI ANTPLASCLH SGYAAGMLRS EGHNVEIIEG FLDGLDYQAI
ERRVKAQKPD ILGVHMVYHW QTDTALYDFL HMVKVEQLSS YITAYGYYPT TDFAEILKQC
QDIDSVILGE PELTFAKVAN AVTNQASLEN LPGLARRDKW GEIVFQRSEL VADLDALPFP
VRTEALFRLP EVNLQGSRGC YGGCTFCYIN PFYGQGSKWR GRSPENIIAE IDDLMAKHRI
KDFYFTDPNF FGPGERGQQR AMRLAALLKS RNLRFGIEAR VNDIHDETIS ALVAAGLRHI
LIGLESGSDR SLKRINKMTT VAQNERAIRT LRQYGIEPNV GFIMFEPDSS LEDIRVNFEF
LKRNDLLKNL AITANLLYHH LIVLKGTKAH RDLQEAGRLK VQGSAYESTV ALTDPKVEVL
ALIMRRITNF LFDRMNGIWG GKVPEPENAQ ERYATINGLL VNLFESTLEM LEVGGRFTEE
QIETLLKSNE KEIDSILL
//
