ID   H5YFV3_9BRAD            Unreviewed;       344 AA.
AC   H5YFV3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:EHR02411.1};
GN   ORFNames=Bra471DRAFT_03164 {ECO:0000313|EMBL:EHR02411.1};
OS   Bradyrhizobium sp. WSM471.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=319017 {ECO:0000313|EMBL:EHR02411.1};
RN   [1] {ECO:0000313|EMBL:EHR02411.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSM471 {ECO:0000313|EMBL:EHR02411.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Pagani I., Brau L., Yates R., O'Hara G., Rui T.,
RA   Howieson J., Reeve W., Woyke T.;
RT   "The Noncontiguous Finished sequence of Bradyrhizobium sp. WSM471.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR   EMBL; CM001442; EHR02411.1; -; Genomic_DNA.
DR   RefSeq; WP_007608507.1; NZ_CM001442.1.
DR   AlphaFoldDB; H5YFV3; -.
DR   HOGENOM; CLU_017452_1_0_5; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000005774; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR012824; CobW.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR02475; CobW; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          253..342
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   344 AA;  36483 MW;  AA9987C11BCC145F CRC64;
     MNSLAKVPVT VVTGFLGSGK TTLIQHLLAN ANGKKLAVLV NEFGSEGVDG EILKSCADAN
     CPEENIIELA NGCICCTVAD DFIPTMEKLL SRSVRPDHIL IETSGLALPK PLLKAFDWPE
     IRSRITVDGV IALADAEAVA AGRFAPDPDA VEAQRAADGN LDHETPLSEV FEDQIACADI
     VLLTKADLAG AAGLEAAKAA ITAEMPRRVP MLAITDGAID ARLILGLGAA AENDLAARPS
     HHDGEEDHEH DDFASVVIDV PEVTDIDTLV ASVQRLAREQ NVLRVKGYIA VEGKPMRLLL
     QAVGERVRHQ FDKPWGMGAR QSKLVVIGEH GNIDEAAIKA GLGI
//