ID H6BDM4_LOLPR Unreviewed; 245 AA.
AC H6BDM4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=glycine hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00012256};
DE EC=2.1.2.1 {ECO:0000256|ARBA:ARBA00012256};
DE Flags: Fragment;
OS Lolium perenne (Perennial ryegrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type);
OC Loliodinae; Loliinae; Lolium.
OX NCBI_TaxID=4522 {ECO:0000313|EMBL:AFA36570.1};
RN [1] {ECO:0000313|EMBL:AFA36570.1}
RP NUCLEOTIDE SEQUENCE.
RA Li H., Hu T., Fu J.;
RT "Identification of genes involved in salinity tolerance in Lolium
RT perenne.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777}.
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DR EMBL; JF747441; AFA36570.1; -; mRNA.
DR AlphaFoldDB; H6BDM4; -.
DR UniPathway; UPA00193; -.
DR GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR001085; Ser_HO-MeTrfase.
DR InterPro; IPR019798; Ser_HO-MeTrfase_PLP_BS.
DR InterPro; IPR039429; SHMT-like_dom.
DR PANTHER; PTHR11680; SERINE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR11680:SF64; SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF00464; SHMT; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00096; SHMT; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000313|EMBL:AFA36570.1};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transferase {ECO:0000313|EMBL:AFA36570.1}.
FT DOMAIN 1..245
FT /note="Serine hydroxymethyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF00464"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFA36570.1"
FT NON_TER 245
FT /evidence="ECO:0000313|EMBL:AFA36570.1"
SQ SEQUENCE 245 AA; 27122 MW; 87C39156C128FAAB CRC64;
PGARYYGGNE YIDMAESLCQ KRALEAFNLD PEKWGVNVQP LSGSPANFQV YTALLKPHDR
IMALDLPHGG HLSHGYQTDT KKISATSIFF ETMPYRLDES TGLIDYDQLE KSAVLFRPKL
IVAGASAYAR LYDYDRMRKI CNKQKAILLA DMAHISGLVA AGVIPSPFEY ADVVTTTTHK
SLRGPRGAMI FFRKGLKEIN KQGKEVKYDF EDKINAAVFP GLQGGPHNHT ITGLAVALKQ
ATTQE
//
