ID H6N1T6_GORPV Unreviewed; 277 AA.
AC H6N1T6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Putative ABC drug resistance transporter, transmembrane protein {ECO:0000313|EMBL:AFA74606.1};
GN OrderedLocusNames=GPOL_c35940 {ECO:0000313|EMBL:AFA74606.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA74606.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA74606.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003119; AFA74606.1; -; Genomic_DNA.
DR AlphaFoldDB; H6N1T6; -.
DR STRING; 1112204.GPOL_c35940; -.
DR KEGG; gpo:GPOL_c35940; -.
DR eggNOG; COG0842; Bacteria.
DR HOGENOM; CLU_039483_2_0_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR000412; ABC_2_transport.
DR PANTHER; PTHR43077:SF8; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRB; 1.
DR PANTHER; PTHR43077; TRANSPORT PERMEASE YVFS-RELATED; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR PIRSF; PIRSF006648; DrrB; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..269
FT /note="ABC-2 type transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF12698"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 29139 MW; 8ABFFC88527AD8E6 CRC64;
MVSGGIPASP EVTPPGGAGV RLDPRPRSLQ QWWALTCRGT SKVFRNGELI FAFISPAFLA
VCFYLPLRSI MNEAPGMNYG QFLMPIIVLQ SVGFAASSAA MRAANDGAEG INTRFRVLPM
SAAIPMLART ATNLVLLAVS LLCAAVACLI IGWRADGGVL GTVGLFALAA TIGVLFSLLA
DGIGLFAGTP EATSQAMTLP TLILGMLSTG FVPLAQFPEW IQPFVRNQPI SQFADSMRGL
DAGTATWELV RPSLAWCVGL LVAAVVLLFL GARKSRG
//
