ID H6N2R9_GORPV Unreviewed; 498 AA.
AC H6N2R9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=NAD-dependent aldehyde dehydrogenase {ECO:0000313|EMBL:AFA74696.1};
GN OrderedLocusNames=GPOL_c36840 {ECO:0000313|EMBL:AFA74696.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA74696.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA74696.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP003119; AFA74696.1; -; Genomic_DNA.
DR RefSeq; WP_014361050.1; NC_016906.1.
DR AlphaFoldDB; H6N2R9; -.
DR STRING; 1112204.GPOL_c36840; -.
DR KEGG; gpo:GPOL_c36840; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_0_1_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154}.
FT DOMAIN 28..494
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 271
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 498 AA; 52591 MW; 3D398D4A0785F9D2 CRC64;
MTAVATELLP RVRDFISSEK KMLIGGEWVS AESGRTFETI DPATARPITS VAHGGAADID
RAVRAARAAF DEGAWVRMKP NERERLLWRV GDILTERAEE FGQLEALDNG KAATIATAVD
TNWSADIFRY NAGLATKITG STVNVSMPFV PGGEFHAYTL REPVGVCGLI VPWNFPLLMA
AFKLAPALAA GNTVILKPAE QTPLTALLLG EVFQEAGFPP GVVNIVTGFG DAGAALSAHD
DVDKIAFTGS TEVGKKIVDA AKGNLKKVSL ELGGKSPNIV FADADFEKAV AGSVAAWMFN
HGQCCVAGTR LFVERPIFDD FTAAVAEAAS QAKIGPGLDP TTELGPLVSQ EQFDRVSGYL
AAGLADGARA LTGGKRWGNE GFFIEPTVFV DVEPDFSIVR EEIFGPVVAA LPFDADTGVA
AAANDSIYGL AAGVWTQDLS KAHKTARAIK AGSVWVNQYN GFDTAMPFGG YKQSGWGREL
GGSAIDLYTQ TKAVNVAL
//
