ID H6NKA7_9BACL Unreviewed; 432 AA.
AC H6NKA7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=argininosuccinate synthase {ECO:0000256|ARBA:ARBA00012286};
DE EC=6.3.4.5 {ECO:0000256|ARBA:ARBA00012286};
DE AltName: Full=Citrulline--aspartate ligase {ECO:0000256|ARBA:ARBA00029916};
GN ORFNames=PM3016_4855 {ECO:0000313|EMBL:AFC31591.1};
OS Paenibacillus mucilaginosus 3016.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1116391 {ECO:0000313|EMBL:AFC31591.1, ECO:0000313|Proteomes:UP000007523};
RN [1] {ECO:0000313|EMBL:AFC31591.1, ECO:0000313|Proteomes:UP000007523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3016 {ECO:0000313|EMBL:AFC31591.1,
RC ECO:0000313|Proteomes:UP000007523};
RX PubMed=22535950; DOI=10.1128/JB.00323-12;
RA Ma M., Wang Z., Li L., Jiang X., Guan D., Cao F., Chen H., Wang X.,
RA Shen D., Du B., Li J.;
RT "Complete Genome Sequence of Paenibacillus mucilaginosus 3016, a Bacterium
RT Functional as Microbial Fertilizer.";
RL J. Bacteriol. 194:2777-2778(2012).
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine
CC from L-ornithine and carbamoyl phosphate: step 2/3.
CC {ECO:0000256|ARBA:ARBA00004967}.
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DR EMBL; CP003235; AFC31591.1; -; Genomic_DNA.
DR RefSeq; WP_014371259.1; NC_016935.1.
DR AlphaFoldDB; H6NKA7; -.
DR STRING; 1116391.PM3016_4855; -.
DR KEGG; pmq:PM3016_4855; -.
DR HOGENOM; CLU_032784_4_0_9; -.
DR UniPathway; UPA00068; UER00113.
DR Proteomes; UP000007523; Chromosome.
DR GO; GO:0004055; F:argininosuccinate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.1260.10; Argininosuccinate synthetase, chain A, domain 2; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR048268; Arginosuc_syn_C.
DR InterPro; IPR048267; Arginosuc_syn_N.
DR InterPro; IPR001518; Arginosuc_synth.
DR InterPro; IPR024074; AS_cat/multimer_dom_body.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11587; ARGININOSUCCINATE SYNTHASE; 1.
DR PANTHER; PTHR11587:SF2; ARGININOSUCCINATE SYNTHASE; 1.
DR Pfam; PF20979; Arginosuc_syn_C; 1.
DR Pfam; PF00764; Arginosuc_synth; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF69864; Argininosuccinate synthetase, C-terminal domain; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Arginine biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007523}.
FT DOMAIN 18..167
FT /note="Arginosuccinate synthase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00764"
FT DOMAIN 187..398
FT /note="Arginosuccinate synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20979"
SQ SEQUENCE 432 AA; 47237 MW; 29500C5B6CD20605 CRC64;
MGQILLSYSQ AQRHRGQKAV MLYSGGLDSM YTALMLKELG LEVHALTADV GQAMPGHLCG
TASALGIRLE IADVRSALCE ENITKGILAN ALFNDHYPIS SSYTRPLIAR EAVKLARKIG
ARLIIHSATP LQNSAARYTT SIMALAPEMD IFCPAVGEYA SREEKMAALA PFLEALGIPF
PLSPSLYSVD ENLWARVIES GPLEDCTQDV PPHGVFEWTA PPEACSTEPL ELTLELREGL
PVALNGQSMP LLAMIGELNG VLGRYGIGRY TGLEDGLFGT KMPELREAPA ACMIHASHVK
LEEAVLSAQE LRIKKSLDRE WTHLVVTGGW YSELKGTLDA AMAAFNRDIT GWVRWRVSPG
QMFCISRSAE KGMYVSRFPA FAQEFQQYSL NSFFQQLGRQ QRLGDGTAIP HDAAAGGEEQ
ADDLILELVL QR
//
