ID H6R1V1_NOCCG Unreviewed; 294 AA.
AC H6R1V1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Transcriptional regulator, LysR family protein {ECO:0000313|EMBL:CCF63030.1};
GN OrderedLocusNames=NOCYR_2253 {ECO:0000313|EMBL:CCF63030.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF63030.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF63030.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF63030.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; FO082843; CCF63030.1; -; Genomic_DNA.
DR AlphaFoldDB; H6R1V1; -.
DR STRING; 1127134.NOCYR_2253; -.
DR KEGG; ncy:NOCYR_2253; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_4_11; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 5..62
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 294 AA; 31465 MW; BF116EFDC42A4139 CRC64;
MTAMDLIRHL RFFVAVADEG HFGRAAAALD MTQPPVSQGL RRLEQFLGVE LVHRTPQGAL
LTSAGRHLLP RSRLLVDDAE RLLAEAQRIA HARGDVHWGV AAALPDPLVT ACVTALRGSA
GAGASVTTTV GSTTDLLADL RAGHSDVAVI EHPALVDGVE AGPVVKIARW LVVPSDHRSA
TAERPTFRML ADLTFAHPPR AGNPPAFDTV IDLLRERGLD ARIDTARDDR AVLAAVAAGT
SFGLTAMAPT PTPGVRWLTM APQALALRLR VVRRPNAAEH AAALDRVLYR ERLR
//
