ID   H6R4H0_NOCCG            Unreviewed;       244 AA.
AC   H6R4H0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=VIT family protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=NOCYR_1239 {ECO:0000313|EMBL:CCF62039.1};
OS   Nocardia cyriacigeorgica (strain GUH-2).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF62039.1, ECO:0000313|Proteomes:UP000008190};
RN   [1] {ECO:0000313|EMBL:CCF62039.1, ECO:0000313|Proteomes:UP000008190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GUH-2 {ECO:0000313|EMBL:CCF62039.1,
RC   ECO:0000313|Proteomes:UP000008190};
RX   PubMed=22461543; DOI=10.1128/JB.00161-12;
RA   Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA   Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA   Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA   Richard Y., Cournoyer B., Blaha D.;
RT   "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT   cyriacigeorgica GUH-2.";
RL   J. Bacteriol. 194:2098-2099(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO082843; CCF62039.1; -; Genomic_DNA.
DR   RefSeq; WP_014349506.1; NC_016887.1.
DR   AlphaFoldDB; H6R4H0; -.
DR   STRING; 1127134.NOCYR_1239; -.
DR   KEGG; ncy:NOCYR_1239; -.
DR   eggNOG; COG1814; Bacteria.
DR   HOGENOM; CLU_038957_3_0_11; -.
DR   OrthoDB; 188924at2; -.
DR   Proteomes; UP000008190; Chromosome.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR   CDD; cd02432; Nodulin-21_like_1; 1.
DR   InterPro; IPR008217; Ccc1_fam.
DR   PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR   PANTHER; PTHR31851:SF87; FE(2+)_MN(2+) TRANSPORTER PCL1; 1.
DR   Pfam; PF01988; VIT1; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008190};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        217..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   244 AA;  25063 MW;  E38504B96C58A9A0 CRC64;
     MDASSELDGA AQHPGEPHTE TLATRLNWLR AGVLGANDGI VSTAGLVVGV AAANTATSTI
     ATAGIAGLTA GAISMAVGEY VSVSTQRDSE RALLAKERRE LRDEPESELA ELTAIYRAKG
     LTPDTARRVA EELTAHDAFT AHAEAELGLN PRELTNPWHA AFSSAVAFTI GALLPLLAIL
     LPPNDLRIPV TFAAVVVALA LTGSISARLG GSRRGRAVVR VVVGGALAMA ITYGIGQLAD
     VSGL
//