ID H6WVW6_CAPHI Unreviewed; 346 AA.
AC H6WVW6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Selenoprotein P {ECO:0000256|ARBA:ARBA00020491};
GN Name=SEPP1 {ECO:0000313|EMBL:AEZ06358.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|EMBL:AEZ06358.1};
RN [1] {ECO:0000313|EMBL:AEZ06358.1}
RP NUCLEOTIDE SEQUENCE.
RA Wang Q., Yue W.B., Zhang C.X., Ren Y.S.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the selenoprotein P family.
CC {ECO:0000256|ARBA:ARBA00010035}.
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DR EMBL; JQ316673; AEZ06358.1; -; mRNA.
DR RefSeq; NP_001272511.1; NM_001285582.1.
DR GeneID; 100861219; -.
DR KEGG; chx:100861219; -.
DR CTD; 6414; -.
DR OrthoDB; 3683808at2759; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR InterPro; IPR007671; Selenoprotein-P_N.
DR InterPro; IPR007672; SelP_C.
DR InterPro; IPR037941; SeP.
DR PANTHER; PTHR10105; SELENOPROTEIN P; 1.
DR PANTHER; PTHR10105:SF3; SELENOPROTEIN P; 1.
DR Pfam; PF04593; SelP_C; 1.
DR Pfam; PF04592; SelP_N; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Selenium {ECO:0000256|ARBA:ARBA00023266, ECO:0000313|EMBL:AEZ06358.1};
KW Selenocysteine {ECO:0000313|EMBL:AEZ06358.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..346
FT /note="Selenoprotein P"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003607812"
FT DOMAIN 23..219
FT /note="Selenoprotein P N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04592"
FT DOMAIN 212..346
FT /note="Selenoprotein P C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04593"
FT REGION 197..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..215
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_STD 59
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 241
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 251
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 282
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 294
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 307
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 309
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 316
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 332
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 334
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 341
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
FT NON_STD 343
FT /note="Selenocysteine"
FT /evidence="ECO:0000313|EMBL:AEZ06358.1"
SQ SEQUENCE 346 AA; 39338 MW; A54D21E04AFCC65E CRC64;
MWRGLGLALA LCLLLTGGTE SQGQSSYCKQ PPAWSIKDQD PMLNSYGSVT VVALLQASUY
LCILQASRLE DLRVKLEKEG YSNISYVVVN HQEISSRLKY VHPKNKVSEH IPVYQQEDDQ
PDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFTYVE DSIKTVYCED KCGNCSLKTQ
EDEDFCKNVS LATKEKTAEA SRRHHHHHRH KGHQRQGHSD NCDTPVGSEN LQLSLPQKKL
URKRCINQLL UQFPKDSESA LSSCCCHCRH LVFEKTGSAI TUQCTENLPS LCSUQGLLAE
ENVIESUQUR LPPAAUQAAG QQLNPTEAST KUSUKNKAKM UKUPSN
//
