ID H8GPT3_METAL Unreviewed; 486 AA.
AC H8GPT3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Efflux transporter, outer membrane factor lipoprotein, NodT family {ECO:0000313|EMBL:EIC29712.1};
GN ORFNames=Metal_1946 {ECO:0000313|EMBL:EIC29712.1};
OS Methylomicrobium album BG8.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomicrobium.
OX NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC29712.1, ECO:0000313|Proteomes:UP000005090};
RN [1] {ECO:0000313|EMBL:EIC29712.1, ECO:0000313|Proteomes:UP000005090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG8 {ECO:0000313|EMBL:EIC29712.1,
RC ECO:0000313|Proteomes:UP000005090};
RX PubMed=23580712;
RA Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA Stein L.Y.;
RT "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT Methylomicrobium album Strain BG8.";
RL Genome Announc. 1:E0017013-E0017013(2013).
CC -!- FUNCTION: Could be involved in resistance to puromycin, acriflavine and
CC tetraphenylarsonium chloride. {ECO:0000256|ARBA:ARBA00037313}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|RuleBase:RU362097}; Lipid-anchor
CC {ECO:0000256|RuleBase:RU362097}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613, ECO:0000256|RuleBase:RU362097}.
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DR EMBL; CM001475; EIC29712.1; -; Genomic_DNA.
DR RefSeq; WP_005371774.1; NZ_CM001475.1.
DR AlphaFoldDB; H8GPT3; -.
DR STRING; 686340.Metal_1946; -.
DR eggNOG; COG1538; Bacteria.
DR HOGENOM; CLU_012817_13_2_6; -.
DR Proteomes; UP000005090; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR Gene3D; 2.20.200.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR InterPro; IPR010131; RND_efflux_OM_lipoprot_NodT.
DR NCBIfam; TIGR01845; outer_NodT; 1.
DR PANTHER; PTHR30203:SF20; MULTIDRUG RESISTANCE OUTER MEMBRANE PROTEIN MDTP-RELATED; 1.
DR PANTHER; PTHR30203; OUTER MEMBRANE CATION EFFLUX PROTEIN; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|RuleBase:RU362097, ECO:0000313|EMBL:EIC29712.1};
KW Membrane {ECO:0000256|RuleBase:RU362097};
KW Palmitate {ECO:0000256|RuleBase:RU362097};
KW Reference proteome {ECO:0000313|Proteomes:UP000005090};
KW Signal {ECO:0000256|RuleBase:RU362097};
KW Transmembrane {ECO:0000256|RuleBase:RU362097};
KW Transmembrane beta strand {ECO:0000256|RuleBase:RU362097}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU362097"
FT CHAIN 22..486
FT /evidence="ECO:0000256|RuleBase:RU362097"
FT /id="PRO_5001439695"
SQ SEQUENCE 486 AA; 53103 MW; 702AE03F32F9F085 CRC64;
MRLVKIALLA TALSLSGCAL LPENGVRAKP IAPPKLAQTL ATDSQAEKIV QEWPQAQWWQ
AFRNPELTRL IETALRDNPG LRVVSARLTQ AEAAADFQAA EMLPSIHASV ELHHRRFSAT
DFYGPNGGKT FTGAYIDPLV FRYHLDLWGK DKAALEAALG QEKAQASELA MSRLLLSTAI
ARSYFSLCAA GEDVELAREL SGKIEEKHQL AELRWQRGLS NQDPVYASRQ QLEAARQRET
RTRHIAQLLR NRLAALAGQG PDWGKSVRAA RNEILGYLPK PETVALGLLA HRPDVAAALW
RVESAAQRVK VAKTHFYPDI DLVGFAGLRS LNLKDLFLSH GASVAYGMGP TLTLPIFEGG
RLEAELKNQE AGYDAAVEGY NDTLLTAVQQ VADSLAEWRQ SSEHEASEAR ALKAAEAESG
LARKRFQAGL SDRDGMIDAE TALIEQRLTA SELHNARLLA AVGLIEALGG GYENSEAAAL
KNRMIR
//
