ID H8GRL6_METAL Unreviewed; 425 AA.
AC H8GRL6;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Nucleotidyltransferase/DNA polymerase involved in DNA repair {ECO:0000313|EMBL:EIC27858.1};
GN ORFNames=Metal_4028 {ECO:0000313|EMBL:EIC27858.1};
OS Methylomicrobium album BG8.
OG Plasmid pMETAL01 {ECO:0000313|EMBL:EIC27858.1,
OG ECO:0000313|Proteomes:UP000005090}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylomicrobium.
OX NCBI_TaxID=686340 {ECO:0000313|EMBL:EIC27858.1, ECO:0000313|Proteomes:UP000005090};
RN [1] {ECO:0000313|EMBL:EIC27858.1, ECO:0000313|Proteomes:UP000005090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BG8 {ECO:0000313|EMBL:EIC27858.1,
RC ECO:0000313|Proteomes:UP000005090};
RC PLASMID=pMETAL01 {ECO:0000313|EMBL:EIC27858.1};
RX PubMed=23580712;
RA Kits K.D., Kalyuzhnaya M.G., Klotz M.G., Jetten M.S., Op den Camp H.J.,
RA Vuilleumier S., Bringel F., Dispirito A.A., Murrell J.C., Bruce D.,
RA Cheng J.F., Copeland A., Goodwin L., Hauser L., Lajus A., Land M.L.,
RA Lapidus A., Lucas S., Medigue C., Pitluck S., Woyke T., Zeytun A.,
RA Stein L.Y.;
RT "Genome Sequence of the Obligate Gammaproteobacterial Methanotroph
RT Methylomicrobium album Strain BG8.";
RL Genome Announc. 1:E0017013-E0017013(2013).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; CM001476; EIC27858.1; -; Genomic_DNA.
DR RefSeq; WP_005375224.1; NZ_CM001476.1.
DR AlphaFoldDB; H8GRL6; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_012348_3_0_6; -.
DR Proteomes; UP000005090; Plasmid pMETAL01.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025188; DUF4113.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF34; PROTEIN UMUC; 1.
DR Pfam; PF13438; DUF4113; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00023199};
KW Plasmid {ECO:0000313|EMBL:EIC27858.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005090};
KW SOS mutagenesis {ECO:0000256|ARBA:ARBA00023199};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Transferase {ECO:0000313|EMBL:EIC27858.1}.
FT DOMAIN 5..189
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 425 AA; 47714 MW; B37B8E92D364BEB9 CRC64;
MRPLLALVDC NNFYVSCERV FRPDLVGKPV AVLSNNDGCI VARSQEVKDL GIKMGVPVFQ
VQNLIQRHKI QLFSSNYTLY ADMSARVMST LEEFTPSMEV YSIDEAFLDL TGISDHDPIA
YGQRIKKNVL RSTGIPVCVG MGPTKTLAKL ANFAAKKWKQ TGGVLDLSDP LRREKLMRIV
PVGEVWGIGS RTAARLNQLG IHTVWDLARQ PPDRIRDQFN VVVARTVMEL NGIPCLELEE
IAPDKQQIVC SRSFSRRLTE YRELSEALAE FCSRAAEKLR HQNSVVGHIS VFIRTNPFNP
NEPQYQRAAG ITLPSATQDT RVIVGTANRL LKELFREGYR YQKCGVQLSR IQPASIPNQT
DLFDSAAFAQ AESGKLMQAV DRINRRFPKG IAVAAAGFDK AWKPKAERIS RRYTTDWRDL
VGVKC
//
