ID H8IAL0_METCZ Unreviewed; 337 AA.
AC H8IAL0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Isocitrate dehydrogenase (NADP) {ECO:0000313|EMBL:AFD00107.1};
DE EC=1.1.1.42 {ECO:0000313|EMBL:AFD00107.1};
GN Name=icd {ECO:0000313|EMBL:AFD00107.1};
GN OrderedLocusNames=Mtc_1353 {ECO:0000313|EMBL:AFD00107.1};
OS Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMCC 1.5162 /
OS HZ254).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanocellales; Methanocellaceae; Methanocella.
OX NCBI_TaxID=1041930 {ECO:0000313|EMBL:AFD00107.1, ECO:0000313|Proteomes:UP000005233};
RN [1] {ECO:0000313|EMBL:AFD00107.1, ECO:0000313|Proteomes:UP000005233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24694 / JCM 17849 / CGMCC 1.5162 / HZ254
RC {ECO:0000313|Proteomes:UP000005233};
RX PubMed=22493204; DOI=10.1128/JB.00207-12;
RA Lu Z., Lu Y.;
RT "Complete genome sequence of a thermophilic methanogen, Methanocella
RT conradii HZ254, isolated from Chinese rice field soil.";
RL J. Bacteriol. 194:2398-2399(2012).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP003243; AFD00107.1; -; Genomic_DNA.
DR RefSeq; WP_014405944.1; NC_017034.1.
DR AlphaFoldDB; H8IAL0; -.
DR STRING; 1041930.Mtc_1353; -.
DR GeneID; 11971481; -.
DR KEGG; mez:Mtc_1353; -.
DR eggNOG; arCOG01163; Archaea.
DR HOGENOM; CLU_031953_0_0_2; -.
DR OrthoDB; 6813at2157; -.
DR Proteomes; UP000005233; Chromosome.
DR GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF77; ISOCITRATE_ISOPROPYLMALATE DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:AFD00107.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005233}.
FT DOMAIN 4..333
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 337 AA; 36577 MW; 6B868B06D77FEF82 CRC64;
MAKKVVVIKG DGVGPELTGL MMKAVKAAGS NVEFIECEAG AGWWEKHGGS SLIPEETWKA
LSESDACFKG PTTTPGGAGS PKSVAVSIRQ KFDLYANVRP IKSYKGLPAP LGEVDFVCVR
EGTEGLYIGE EIQLTNDVFI AIRKITRPAC RRVAKYAFEE AMRRGWKSVV AIHKSNILKK
TDGAFLEECG KVKADYPGIE LEEYHVDNVA QQLVKNPAIY NKKVLLSTNL FMDILSEECS
ALVGSIGLIY SANIGDGYAM FEPAHGSAPK YAGMDKVNPV ATVLAGAWML DYLGEKIQSQ
AIFEATEKVI AEKRHVTYDM GGSARSSEMV DAIIRNL
//
