ID H8INQ0_MYCIA Unreviewed; 181 AA.
AC H8INQ0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Thiopurine S-methyltransferase (Tpmt) superfamily protein {ECO:0000313|EMBL:AFC43998.1};
GN OrderedLocusNames=OCU_27790 {ECO:0000313|EMBL:AFC43998.1};
OS Mycobacterium intracellulare (strain ATCC 13950 / DSM 43223 / JCM 6384 /
OS NCTC 13025 / 3600).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=487521 {ECO:0000313|EMBL:AFC43998.1, ECO:0000313|Proteomes:UP000008004};
RN [1] {ECO:0000313|EMBL:AFC43998.1, ECO:0000313|Proteomes:UP000008004}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600
RC {ECO:0000313|Proteomes:UP000008004};
RX PubMed=22535933; DOI=10.1128/JB.00295-12;
RA Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Lee J.H., Chun J., Kook Y.H.,
RA Kim B.J.;
RT "Complete genome sequence of Mycobacterium intracellulare strain ATCC
RT 13950T.";
RL J. Bacteriol. 194:2750-2750(2012).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361}.
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DR EMBL; CP003322; AFC43998.1; -; Genomic_DNA.
DR RefSeq; WP_009952431.1; NZ_CP076382.1.
DR AlphaFoldDB; H8INQ0; -.
DR GeneID; 77301712; -.
DR KEGG; mia:OCU_27790; -.
DR PATRIC; fig|487521.10.peg.2793; -.
DR eggNOG; COG2264; Bacteria.
DR HOGENOM; CLU_056435_5_3_11; -.
DR Proteomes; UP000008004; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43464; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43464:SF90; TELLURITE METHYLTRANSFERASE; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AFC43998.1};
KW Transferase {ECO:0000313|EMBL:AFC43998.1}.
FT DOMAIN 44..132
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 181 AA; 18787 MW; EED2ED24D562B37C CRC64;
MGESDRQRWD ERYAAKAPPS LDSVGPPGVF AGHAREFPTA GTALDLACGQ GTGSVWLALR
GLHVLGLDIS AVAVAHAREL ARRAAVADRC RFDVVDLDNG LPAGAPADVI LCCKFRDRRL
DRAIIERLAP GGLLAIAALS EVGASAGPFR AAPGELTAAF AELTPIAAGE GAGQAWLLAR
R
//
