ID H8IRD3_MYCIA Unreviewed; 468 AA.
AC H8IRD3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Transmembrane protein {ECO:0000313|EMBL:AFC44254.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:AFC44254.1};
GN OrderedLocusNames=OCU_30350 {ECO:0000313|EMBL:AFC44254.1};
OS Mycobacterium intracellulare (strain ATCC 13950 / DSM 43223 / JCM 6384 /
OS NCTC 13025 / 3600).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=487521 {ECO:0000313|EMBL:AFC44254.1, ECO:0000313|Proteomes:UP000008004};
RN [1] {ECO:0000313|EMBL:AFC44254.1, ECO:0000313|Proteomes:UP000008004}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600
RC {ECO:0000313|Proteomes:UP000008004};
RX PubMed=22535933; DOI=10.1128/JB.00295-12;
RA Kim B.J., Choi B.S., Lim J.S., Choi I.Y., Lee J.H., Chun J., Kook Y.H.,
RA Kim B.J.;
RT "Complete genome sequence of Mycobacterium intracellulare strain ATCC
RT 13950T.";
RL J. Bacteriol. 194:2750-2750(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003322; AFC44254.1; -; Genomic_DNA.
DR AlphaFoldDB; H8IRD3; -.
DR KEGG; mia:OCU_30350; -.
DR PATRIC; fig|487521.10.peg.3048; -.
DR eggNOG; COG0664; Bacteria.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_032479_3_0_11; -.
DR Proteomes; UP000008004; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR016846; cNMP-bd_ion_channel.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR30566:SF25; INNER MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF026673; UCP026673_ion_chan; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:AFC44254.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..433
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 468 AA; 50463 MW; 03B79D8E611A769C CRC64;
MDSSSLYWAA GVVIGLPLLL IALTEWHQSL VRKDSPLARP AFLLRSYLIP LGALLVLLVN
VARMPAQFTS VRVLATVFGF VVLVLLLSGL NATVFEGAPQ GTWRQRIPGI FLDVTRFVLI
GVGLAVIFSY VWGVRVGGLF TALGVTSVVI GLMLQNSVGQ IVSGLFMLFE QPFRIGDWLD
TPAARGRIVE ANWRSVHIQT GRGLQITPNS VLATTSFTNL SRPPGGHQLA ITTTFSEVDP
PDRVCALLER VANALPQRRP NAVAAATPAG AAEYLLTVGL RSPADDSAAQ ATFLRWLWYA
GRREGLRLDG AEDDISTPER IEKALRTVVA PALRLSQPDQ QSLASHARIV RYGANEIVEH
AGRVPDKMTF LLAGGVRLTA TARDGTAVAV GGLDEGSFLG VTALTRQPNL SDAQAVDEIT
ALEIDRDHLV ELVTSKPLLL QDLGRAIDER RARVHEAMGQ EFALSATP
//
