ID H8MK64_CORCM Unreviewed; 427 AA.
AC H8MK64;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Membrane fusion component of tripartite multidrug resistance system {ECO:0000313|EMBL:AFE08650.1};
GN Name=emrA {ECO:0000313|EMBL:AFE08650.1};
GN OrderedLocusNames=COCOR_00896 {ECO:0000313|EMBL:AFE08650.1};
OS Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)
OS (Myxococcus coralloides).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Corallococcus.
OX NCBI_TaxID=1144275 {ECO:0000313|EMBL:AFE08650.1, ECO:0000313|Proteomes:UP000007587};
RN [1] {ECO:0000313|EMBL:AFE08650.1, ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RX PubMed=22582372; DOI=10.1128/JB.00397-12;
RA Huntley S., Zhang Y., Treuner-Lange A., Kneip S., Sensen C.W.,
RA Sogaard-Andersen L.;
RT "Complete Genome Sequence of the Fruiting Myxobacterium Corallococcus
RT coralloides DSM 2259.";
RL J. Bacteriol. 194:3012-3013(2012).
RN [2] {ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RA Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.;
RT "Genome sequence of the fruiting myxobacterium Corallococcus coralloides
RT DSM 2259.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003389; AFE08650.1; -; Genomic_DNA.
DR RefSeq; WP_014393747.1; NC_017030.1.
DR AlphaFoldDB; H8MK64; -.
DR STRING; 1144275.COCOR_00896; -.
DR KEGG; ccx:COCOR_00896; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_1_7; -.
DR InParanoid; H8MK64; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000007587; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00022519};
KW Reference proteome {ECO:0000313|Proteomes:UP000007587}.
FT DOMAIN 67..113
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 233..355
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 99..133
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 427 AA; 44703 MW; B7C0E8F9D3702A28 CRC64;
MTTRTAPSLE AAPSTEAPAV TKPAKRSRAR QVLPILVGVA VLGGGARFLL THGHESTDDA
QVEGRIANVS PRVAGQVARV LVHDNQTVKA GDVVVELDHA DLDARLEVAR ADVMSAEAQL
SNAQAQLTLT EANAGANLRQ ARAGVTQASS GISSSKAALD QARADVTASE ARFKLAETDL
GRIKQLREQG AVAQADLDAR QASYDQAKAA LDQSRARLTS TEAGIQSSSG GLEAAQGKLS
AAETAPVQVQ AAQAALKLAE ARLKQTHGAL TLAELAVSYA QVRAPVDGVI SRRTVEVGQM
VGPERPLMAV VPQNDIWIVA NFKEDQVGEM RPGQPVELEV DAFGSHSFKG HVDSLAGASG
ARFALLPPDN ASGNFVKVVQ RIPVLIRFDG DLKDLPIKPG MSAYVTVDTG AKPEPQKSAA
VDTRKAE
//
