ID H8MSA6_CORCM Unreviewed; 707 AA.
AC H8MSA6;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=aminodeoxychorismate synthase {ECO:0000256|ARBA:ARBA00013139};
DE EC=2.6.1.85 {ECO:0000256|ARBA:ARBA00013139};
GN Name=pabB {ECO:0000313|EMBL:AFE09721.1};
GN OrderedLocusNames=COCOR_02572 {ECO:0000313|EMBL:AFE09721.1};
OS Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)
OS (Myxococcus coralloides).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Corallococcus.
OX NCBI_TaxID=1144275 {ECO:0000313|EMBL:AFE09721.1, ECO:0000313|Proteomes:UP000007587};
RN [1] {ECO:0000313|EMBL:AFE09721.1, ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RX PubMed=22582372; DOI=10.1128/JB.00397-12;
RA Huntley S., Zhang Y., Treuner-Lange A., Kneip S., Sensen C.W.,
RA Sogaard-Andersen L.;
RT "Complete Genome Sequence of the Fruiting Myxobacterium Corallococcus
RT coralloides DSM 2259.";
RL J. Bacteriol. 194:3012-3013(2012).
RN [2] {ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RA Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.;
RT "Genome sequence of the fruiting myxobacterium Corallococcus coralloides
RT DSM 2259.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the anthranilate
CC synthase component I family. {ECO:0000256|ARBA:ARBA00005970}.
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DR EMBL; CP003389; AFE09721.1; -; Genomic_DNA.
DR AlphaFoldDB; H8MSA6; -.
DR STRING; 1144275.COCOR_02572; -.
DR MEROPS; C26.A25; -.
DR KEGG; ccx:COCOR_02572; -.
DR eggNOG; COG0147; Bacteria.
DR eggNOG; COG0512; Bacteria.
DR HOGENOM; CLU_006493_0_1_7; -.
DR InParanoid; H8MSA6; -.
DR OrthoDB; 9803598at2; -.
DR Proteomes; UP000007587; Chromosome.
DR GO; GO:0046820; F:4-amino-4-deoxychorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005802; ADC_synth_comp_1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00553; pabB; 1.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF18; AMINODEOXYCHORISMATE SYNTHASE; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF56322; ADC synthase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 3: Inferred from homology;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Reference proteome {ECO:0000313|Proteomes:UP000007587};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..192
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT DOMAIN 233..373
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 421..675
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 199..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 87
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 175
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 707 AA; 77928 MW; 914BFCB50EA72B6A CRC64;
MRAVRLRTLI IDNHDSFTFN LFQLLAEVGG TEPLVVRNDE RSWRELRELT FDNIVISPGP
GRPDHPTDFG VCRDALLEAD VPILGVCLGH QGLGHVHGAR IQHAPEVMHG RLSPVRHTGT
DLFQGLPQDF QVVRYHSLCL ARPLPEDLVE TAWAPDGVLM ALRHASLPRW GVQFHPESIA
TTHGRQLLAN FVRLSRAHHV PRPSRPPEAP QEKAPLPPPG TFRVHHRKLR LDADPEQAFV
ALLGGSDHAF WLDSSRVEAG LSRFSFMGDA TGPHSAVIHY QVNPRRLTVR RSQGTEEHST
ELFEFLQQEL TRLRVVPSGL PFDFQGGFVG SLGYELKHDC GATTPHASPD PDASLILADR
LLAWDHLERT VYLVALAPEH EAAQVQAWFD ATESSLRALP PLAPLEPRSG APFPVRLARD
RETYLADIQR CLEQLHEGET YEVCLTNKLL ARTHVDPLDL YRSLRRLNPA PYAAYLRMGP
QGIACSSPER FLRVDAERWV ESKPIKGTLR RGSTPAEDDR LRQQLGSQEK DRAENLMIVD
LVRNDLGRVC EVGSVHVPRL MHVESYATVH QLVSTIRGHL RPGLTAVDAV RAAFPGGSMT
GAPKERTMEL IDRLEGEARG VYSGAIGYFS ATGAADLNVV IRTAVVRPGE VSIGAGGAIV
ALSDPAAELD EMLLKSRVVL NALCTALGRP DGLPEPGADS RAWTAPD
//
