ID H8MU17_CORCM Unreviewed; 10504 AA.
AC H8MU17;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000313|EMBL:AFE09749.1};
GN Name=pcbAB {ECO:0000313|EMBL:AFE09749.1};
GN OrderedLocusNames=COCOR_03928 {ECO:0000313|EMBL:AFE09749.1};
OS Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)
OS (Myxococcus coralloides).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Corallococcus.
OX NCBI_TaxID=1144275 {ECO:0000313|EMBL:AFE09749.1, ECO:0000313|Proteomes:UP000007587};
RN [1] {ECO:0000313|EMBL:AFE09749.1, ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RX PubMed=22582372; DOI=10.1128/JB.00397-12;
RA Huntley S., Zhang Y., Treuner-Lange A., Kneip S., Sensen C.W.,
RA Sogaard-Andersen L.;
RT "Complete Genome Sequence of the Fruiting Myxobacterium Corallococcus
RT coralloides DSM 2259.";
RL J. Bacteriol. 194:3012-3013(2012).
RN [2] {ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RA Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.;
RT "Genome sequence of the fruiting myxobacterium Corallococcus coralloides
RT DSM 2259.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP003389; AFE09749.1; -; Genomic_DNA.
DR STRING; 1144275.COCOR_03928; -.
DR KEGG; ccx:COCOR_03928; -.
DR eggNOG; COG0318; Bacteria.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_222626_0_0_7; -.
DR InParanoid; H8MU17; -.
DR OrthoDB; 5475787at2; -.
DR Proteomes; UP000007587; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 4.
DR CDD; cd17652; A_NRPS_CmdD_like; 1.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR CDD; cd05931; FAAL; 1.
DR CDD; cd19531; LCL_NRPS-like; 8.
DR Gene3D; 3.30.300.30; -; 10.
DR Gene3D; 3.40.50.980; -; 18.
DR Gene3D; 1.10.1200.10; ACP-like; 10.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 9.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 9.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR040097; FAAL/FAAC.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR020802; PKS_thioesterase.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 9.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 10.
DR Pfam; PF13193; AMP-binding_C; 9.
DR Pfam; PF00668; Condensation; 9.
DR Pfam; PF00550; PP-binding; 10.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 10.
DR SMART; SM00824; PKS_TE; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 10.
DR SUPFAM; SSF47336; ACP-like; 10.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 18.
DR PROSITE; PS00455; AMP_BINDING; 10.
DR PROSITE; PS50075; CARRIER; 10.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 9.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AFE09749.1};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007587}.
FT DOMAIN 620..697
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1670..1745
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2717..2792
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3767..3842
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4828..4902
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5900..5975
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 6956..7031
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8011..8086
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 9075..9150
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 10145..10220
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1651..1670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 9373..9393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 10504 AA; 1146312 MW; 348ADBE9C8CF6FB7 CRC64;
MGSSLSRSPE LTPSHSTLVE ILRSRAESWP EQPLYTFLDD AGQEDGTLSY AGLDARARRI
AVALRKVAKP GERVMLLYPP GLEYVAGFFG CLYAGLIAVP AYPPDPMRLE RTLPRLRAII
QDANATVVLT TSGILSMTEF VFEQAPDLRS LHWVGTDEIP AGGEAEWTPP EVDASTLAFL
QYTSGSTGSP KGVMLSHGNL AHNLALITDA FELGPTSSAV IWLPPYHDMG LIGGILTPLY
ATFHAALMSP LTMLKNPRVW LEAITRYKAT ISGGPNFAFD LCVRRIPAEE RQSLDLSSWK
VAFTGAEPIR PATLDRFEQA FGPHGFKREF FFPCYGLAEA TLLVSGGRVE APPVSCALDA
PALEQRRAVL VDAAKPEARV LVGCGDERPG HPVVIVDPQT REACAPGGVG EIWVRGPSVA
LGYWNKPEAT AEAFQARVKG TDEGPFLRTG DLGFMRDGEL YVTGRAKDLI IIRGRNHYPQ
DIEQTVEESH PALRAGSVAA VSLEVAGEER LVVVQEIDLR KAGNLRKQVD MAEAAVKEIR
QRVAERHEVQ VHAVALIEPG SIPKTSSGKI QRHACKAQFL ADELRTVLVW REPGFEEAEE
TEAAESSEPA AAPVREDVPE AARATLTWLV ERVAEQLKVP AKTVDVREPI TRYGLDSLSA
VELAHAVEKG LGIALPMELL LQGPSLVELA KRITASKQEP KAAVLAPRPR GATQPLSFAQ
QRLWFLDRLE QGSALYSIPG AVRLDGALDA ESLRRSLEEI VRRHESLRTT FREENGEAVQ
LIHPAKAFEL PVVDLTGFPE ASREAEARRC VDEEAVRPFD LGSGPLVRAR LLKLGEAKHV
LLVTMHHIVS DGWSMGVLVR EVAALYDAFR GGRGSPLPEL RVQYADFAQW QREWLLGGVL
EKQVGYWKQR LAGAPAVLEL PTDFARPAAQ TYRGATVPVK LGAELGKALG ALAKKEGVTP
YMLLLAAFQV LLGRYSGQDD ISVGSPITGR SRAETEGLIG FFVNTLVLRT KLEGNPSFRA
LLAQVKETTL GAYAHQDVPF EKLVEELQPQ RSLSHAPLFQ VMFVLQQDVL PHFRLPGVEL
SPYEVESKTA KFDLTLYLTE TAGGLEGTLE YNTDLFAAAT ARRMMEHLRV LLESLLTDPG
AKLSDLSLMG AQEKQTLLKD ISGTDLSAPV SGTMQALFEA QAARTPDAPA VHFDGQVLTY
AQLDAQANQL AHHLRGMGVG PDTLVGVSLE RSARMVVALL GVLKAGGAYV PLDPAYPRDR
LGWMLEDAQA PVLLTQQKLL GVLPEHSAKA VCVDADWAVI ATQPTTPVAT STGVGNLAYV
LYTSGSTGRP KGVAIEQRSV VAFLHWSTAA FTKQQLAGVL AATSLNFDLS VFEVFAPLSS
GGAVIVAENA LALPTLKDAS RVTLVNTVPS AMAELVRSQG VPESVRTVNL AGEPLLNRLA
KPLYGLKNVE GVYNLYGPTE DTTYSTYTRV EKDAAREPTI GRPLTGSRAY VLDAWLRPVP
QGVPGELYLA GAGLARGYLA KPSLTAERFV PNPFSEQPGA RMYRTGDRVR WLATGELEYL
GRIDFQVKVR GFRIELGEVE SALASQPGVR ESVVVVREDV PGDKRLVAYV AGTSLDVAEL
RKGLKARLPE YMVPSAFVVL NALPLTPNGK VDRKSLPVPE GQASQSQYVA PRTATEEQVA
TLFAQLLRVE RVGAEDSFFE LGGHSLLAMQ LVSRLRTAFG IEVPLRSLFE LSTVASLAAF
IDGKKQQAEG ANLPPLKRVV REGSLPLSFA QQRLWFLDRL EQGSALYNIP GAVRLEGALD
VEALRLTLQE IVARHESLRT TFREENGEAV QSIQAAGRMD LPVVDLSTVA EAETQRLVNE
EAVRPFDLGT GPLFRAQLLK LGEAKHVLLV TMHHIVSDGW SLGVLVREMA ALYEAHSQGR
AMPLPELAVQ YADFAQWQRE WLLGGVLEKQ VGYWKQQLAG APALLELQTD FARPAVQTYR
GATVPVKLGA DLSRTLNALA KQEGVTPYQL LLAAFQVLLA RYSGQDDISV GSPIAGRTQA
ETEGLIGFFV NTLVLRTKLA GNPTFQQVLK QVRETTLGAY AHQDVPFERL VEELQPQRSL
SHAPLFQVMF ALQQDVLPHL KLSGMELSPY EVESKTAKFD LTLFLTETAG GLEGTLEYNT
DLFTAATAQR MTEHLRVLLE SVAVRPMAKV SDLALMSAQE KQTLLMDVSG TDLPAPVSGT
MQALFEAQVA RTPDAAAVYF DGQVLTYAQL EAQANQLAHH LRGMGVGPDT LVGVSLERSA
RMVVALLGVL KAGGAYVPLD PAYPRDRLGW MLEDAQAPVV LTQQKLLGVL PEHSARNVFL
DTDWETISKN PVSRVDPRTG VRNLAYVLYT SGSTGRPKGV AIEQRSVVAF LHWATAFFTP
QQLSGMLAST SLNFDISVFE VFAPLSVGGA VIVAENALAL PTMKDASRVT LVNTVPSAMA
ELLRSGGVPD SVRTVNLAGE PLLNRLAQAA YGLKNVEAVY NFYGPTEDTT YSTYLRVEKG
AAREPTVGRL LTGSRGYVLD AWLRPVPQGV PGELYIAGAG LSRGYLAKPA LTAEKFVPNP
FSQEPGARMY RTGDRVRWLA NGELEYFGRI DFQVKVRGFR IELGEVESVL STQPGVRESV
VVVREDVPGD RRLVAYVAGA SLDVAELRKG LKARLPEYMV PSAFVVLNAL PLNPNGKVDR
KSLPVPEAQS SQGQYVAPRT ATEEQVATLF AQLLRVERVG AEDSFFELGG HSLLAMQLVS
RLRTAFGAEV PLRSLFELST VASLAAFVDT AVSGRDASKA PAITARPRSA TESLSFAQQR
LWFLDQLEQG SAFYNVAGGV KLEGALHVDA MRRALEEIVR RHESLRTTFR DENGQAVQVI
HPAKVFELPV VDVSGAQDTE ARRLAEEEAT RPFDLGTGPL FRAKLLKLGE AKHVLLVTMH
HIVSDGWSMG VLVREVAALY EAQVLKQKSP LPELAVQYAD FAQWQREWLL GGVLEKQVGY
WKQQLAGAPA VLELPTDFAR PAVQTYRGAT VPVKLGADLS RTLNALAKQE GVTPYQLLLA
AFQVLLSRYS GQDDISVGSP IAGRTQAETE GLIGFFVNTL VLRTKLTGNP SFQQVLKQVR
ETTLGAYAHQ DVPFEKLVEE LQPQRSLSHA PLFQVMFALQ QDVLPHLKLS GVELSPYEVD
AKSAKFDLTL SLTETAGGFE GTLEYNTDLF TAATAQRMTE HLRVLLESVA VRPMAKLSQL
ALMGPQERHQ VLVAWNDTRA DVTGDVTFPV LFEAQVRRAP DSQALVFEDA SLTYAQLDAR
ANQLAHHLRT LGVGPEVRVA LCVERSLELA VAMLGIQKAG GAFVPLDPSY PRERLSFMLE
DSGAPVLVTQ SSLSQQLPAD GLRVVRMDVE AAHLRTLPET APASSANADT LAYVIYTSGS
TGRPKGTLLP HRGLNNTARQ AAAAKGLGTG RRALQYAASS FDASVWEVFS TLVSGATLVL
APRDRLLPDE PLRTLLKSQR ISTVTLTPSV LAQLSTDGLD GLSTIVSAGE ALSVEMARKW
GQGRTLINAY GPTETTVCAT LTHGGVRAER LTIGKPLANV QVYVLDALHH PVPVGVAGEL
YVAGEGLARG YQGRPDMTAE KFVPNPFSNE PGARLYRTGD RVRWLAEGEL EYLGRIDHQV
KVRGFRIELG EIEAVLLRHA DVREAAVVVR EDVPGDKRLV GYVVPQPGRT VDAASLRKHL
KDGVPEYMVP SAFVVLDALP MTPAGKVDRK ALPAPTGALT RPDAYVAPRT PTETRVAALF
ARVLTVERVG AEDSFFELGG HSLMATQLVS RLRGEFQVEL PLRALFESPT VAALAARVDE
ATGAERKFKT PPLKPASREG SLPLSFDQER LWLFEQLTPG TPIYNVPSAA RLSGDLDVEV
LRRGLEEIVR RHEALRTVFH QDASGSPVQV VLPAKPFVLP VVDLSSLPAD KAEAEARKHL
NAEAARPFDL VQGPLLRAQL LKLSAREHVL CLAMHHIVVD GWAVGVFMNE LQALYTAFSR
GEPSPLPALP VQYADYTLWH RQWLSGDVLE QQIAWWKKQL AGAPRIALRT DAPRPAGDRF
HGDSRRFHLS PDLTSRIEAL GRGEGATLFM VLLAAFDALL HRRTGQDDIV VGTDIANRAR
EELESLVGFF TNQLVLRTQV SGDLSFRALL DRVRKGTLDA YEHQDLPFGT LVQALKPPRE
PGGQLFNVKF VLENAPLPPL QLPGLELSLL DAETNGTAKW DLLVVVFPWQ GGLTVTVEHN
TDVLDRASVE RLFAHFESLL RAVVENPEHR IGTLPLLTQD ERGTLAAWND RPRTYPHGQP
VSRVFEAQAA RAPDAVAVSF EGETLTAGQL NARANQLAHH LRALGVRPGK RVGVSLERSL
DLVVAVLGIA KAGGAYVPLD PSFPTERLSM LIEDAGLSAL VSVSAIADEL PAQWLQVVCL
DDDAATLAKR PDTNLDTAPT GEDELYVLYT SGSTGRPKGV SVPHRAVVRL VCGPEWVSLS
SKEVFLQLAP LAFDASTFEL WGAMLNGAKL AVFPPRAPTL DELGEVITRE GVSTLWLTAG
LFHQMVDGNL DGLRPVRQLL AGGDVLSPAH VLRVMEQLPG CRVINGYGPT ENTTFTACYP
VEDAGALGIS VPIGRPINGT RVHVLNASLE PVPLGAPGEL FAGGDGLAHG YLNQPELTAE
KFIPDPFSTV PGARLYRTGD QVRFRADGSL EFLGRIDQQV KVRGFRIEPG EIETALRGHP
SVLDVTVAVQ EVAGEKALVA YVVTEEGAEP LGVDTMRSFL HDKLPAYMVP TALMELDAMP
LTPNGKVDRR ALPVPGSERP QMSTAYAAPR TMEETALCEV WAEVLGVERV GIDDSFYDLG
GDSIRSIQLI AKLRERGLDL PMVELLRQPT IRALGNLVHA APSKAAAQAV PGSEPFSLLS
DADRARLPAD VEDAYPVAVL QAGMLFQSEL DQASGMYHDA TSYHLEMALD EAKMRQLLAE
LARRHAILRT SFDLTGYEQP LQFVHREAQV PLELHDVRHV PAAEQDALLR KLVEEDRCRP
FDWSRAPLLR FAIYRRTEKT LQFSLIFHHA ILDGWSLATL LSELFRGYVN LLRGTPAPEA
APLAVTYRQF VALEHQSLTS GEGEQFWKSR LSEVDRPAPR APLPAGQEPV LSMRQVDVPA
ALQDGLQRVA QAANVPLKTV LLAAHLRVRA LMEGQRSVVT GVVSNGRPET ADSERMVGLF
LNSIPFPVTL EDGSWLDLVR QVSKADGDIW PHRRYPMGRL QQQLGGQRLF ETIFNFVHFH
VAGGLSQLEG VRLLEETPST AWMELPLSTL FLQRPDTGAL MLVLRTNGTQ RDADQTEALA
GYYFRALEAM AANPHARHEH ARLLPDAERQ KLLVEWNATG AQPAGDTCVH ERFAVHAART
PDAVAVVCDD GQLTYGELNR RANQLAHWLR ARGVGPDARV GLLTERTPDA IVGMMGILKA
GGAYVPLDPS HPPERLRTVL EDASASLVVT QASLAAHVAD ASRGHVCLDS DAALLSRERE
DDPKRLGDAS SLAYVIFTSG STGRPKGVAI EHRQLNHYVE GVTLRLELPP AASFASVSTL
AADLGHTAVF PTLSGGGTLH LISRDRASDP AALGDYFQRH AVDCLKIVPS HLTALLSSPS
PERVLPRKRL VLGGEASDPA LVARVHALVP GLEVFNHYGP TETTVGVLTW KVERGTQLSA
TASVPLGRPL PNARMYVLDA ALQPVPVGVP GELFIGGAGV ARGYLGQPGL TMERFLADPF
HPEPGARVYR TGDRVRYLPD GALEFLGRVD FQVKVRGFRI ELPEIEAAMS GLPGVAEVVV
LAREDVPGDK RLVAYVVAVP GHTLEAGALR QGLKSRLPDY MVPSAFVMLD ALPLTSNGKV
DRRALPAPEK ETEAGRAHVA PRTPTEELIA GLWSKLLGVE RVGVKDDFFA LGGHSLLATQ
MISRIRSAFR VELPLRALFE ATTVETLSAR VDEAVRQGFG LEAPAIVPLS REHTLPLSFA
QQRLWFLDQL EPDSAFYNIA APVMLDGSLE VAPLEQAFTE LVRRHEVLRT TFRAEGGNPV
QVVHPAAPMP LPLVDLTHLP EAEREAKAQR LADEDAGRPF NLATGPLLRA TLVRISDVRH
MLLLTVHHIV SDGWSRGVLV REVAALYEAF RQGKPSPLPE LPVQYADYSG WQRGWLQGDV
LKKQVGYWKQ QLTGAPSALE LPTDFPRPAV QTYRGETLPF TLPRELSDAL RALALKEGVT
PYMLLLTAWQ VLLARHAGQD DVTVGSPVAG RGRMETEGLI GFFINTLVLR TRLEGDPSFR
QVLARVRESV LGAHAHQEVP FEKLVEELQP VRDTSRSPLF QVWFVLHQEL AAKLSVPGLT
LSAYEAEART AKFDLALSML DAADGFVGRL EYNSDLFARA TAERMMARLH VLLAGIVAKP
ESAVGELPLL SAEERHQVLV GWNSVRAELP REATIHSLIE AHAEATPDAV ALVYEDQSLT
YAELDVKANQ LAHHLRRRYV GREVRVALCL ERSLDLVVGM LGILKAGGAF IPLDPSYPVE
RLDYMLSDSG APVLVTQESL MDSLPTDGRL TIQLDMDVDA IERMPEEAPR SGTSAHNLAY
VIYTSGSTGR PKGTLLQHEG LVNTALRAAA AKRVGPGSRV LQYAASSFDA SVWEIFSTLA
AGATLVLAPR DRLMPDEPLR TLLKEQGITT ATLTPSVLAQ LSTEGLEGLR SVVSAGEALS
VELARKWGAG RLMINAYGPT EATVCATLTE GGVNPERITI GKPWANAQVY VLDAAQRPVP
VGVAGELYIG GVALARGYQG RPDLTAEKFV PHPFSQEPGA RVYRTGDRVR WLATGELEYL
GRIDFQVKVR GFRIELGEVE SVLLHHTDIR EAAVVVREDV PGDKRLVAYV VAQEDTELDV
AELRRHLKGE VPEYMVPSAF VVLEALPMTP AGKVDRKALP APSDARMERS EAEFAAPRTP
TEKMLATVWT EILDVKRVGV RDNFFDLGGH SLLATQVASR IREAFGVELP LRALFEAPTI
ADLAQRVDQS VRSEQGLQAP PIVPLPREGS LPLGLAQQRL WFLDQMEPDS AFYNIVLPVR
LEGELDLGVL ERTFTELVRR HESLRTTFHA EGDQPVQRIH APAPASLNVV DLSGLPDAER
EAEAKRLADA ETNRGFKLAT GPLMRALILR MSQTEHVLLL SLHHIITDGW SMSLLVREIA
AIYAAFREDK PSPLPELPVQ YADYAGWQRD WLRSDVMGKH VEYWRQQLSG APSALELPTD
FPRPAVMTYS GGGVAVKVPQ ALSQRIKALC REKGVTPFMF LLAAWQVLLA RHAGQDDISV
GSPAAGRGHS STEGIIGFFV NTLVLRAKLE GNPSFRDVLT QVRDTVLSAH VHQEVPFEKL
VEELHPVRDT SRSPLFQAMF VLQAEELSGQ VSVAGLTLKT FEAEARTAKF DMSLSLADAS
EGFLGRLAYN SDLYSRVTAE RLVQHFVMML EGIATDMDQR VMALPLMTED EARQELVVWN
DTRVDFPREA CIQSFIQAHA RATPDAVALV YEDTSLTFAQ LDAKANQLAH HLRTLGVAPE
VRVALCLDRS LDLVVGMLGV LKAGGAFVPL DPAYPIDRLD YMLEDSGATV LVTRGEPMPG
LHAEDRVGLH LDDVRDVLKA MPTTAPSVNL TSANLAYVIY TSGSTGRPKG TLLQHQGLVN
TAIQAGRAHR YAPGSRVLQY AASSFDASVC EVFGTLVAGA TLVLAPRDRL LPDEPLRTLL
QQQRITAVTL TPSVLAQLGT EGLEGLRTVI SAGEALSVEL ARKWGEGRLM INAYGPTEAT
VCATLTENGA NPERLTIGKP WANVQVYVLD DALRPQPAGV PGELYVAGVG LARGYQGRPD
LTAERFIPNP FSQEPGARLY RTGDRVRWTS SAELEYLGRI DSQVKVRGFR IELGEVESVL
LHHAEVREAA VVVREDAPGD KRLVAYVVPQ AAGTLDAVEL RRHLKSEVPE YMVPSAFVVL
EALPLTPAGK IDRKALPAPT GEVSRTRTFV APRTPTEELL AALFAQLLGV ERMGVEDHFF
EMGGHSLMAT RLASRIREAF DVELPLRTLF EAPTVTDLAR RVDALVAQGR GVKAPPLVAL
PRAERMPLSF AQQRLWFLNQ LEPDSAFYNL PLPVRLEGTL DVSALERAFT ELVRRHESLR
TTFPMRDGQP AQVVHPAVTV SLPVVDLSGQ PEDVREAEAQ RRANEEAQRP FHLANGPLLR
VKLLKLEAQR HVLLATMHHI VSDGWSMGVL VREMAALYEA YASGRAPSLP ELPVQYADYA
GWQRGWLQGD VLAQQMAYWK QQLTGAPAAL ELPTDRPRPA VQTYRGASVN LRVGKPVTDT
LKALALKEGA TPFMVLLAAW QVLLARYSGQ DDVSVGTPIA GRGRTETEGL IGFFVNTLVL
RTKLEGNPSF RALLAQVKET TLGAYAHQEV PFEKLVEELA PTRDTSRTPL FQVLLSFQNA
PVPELEVKGL TLRAVPLEHR TAQFDLNMTL SEVDGELRGA MEYNSDLFDA GTAERMLEHL
RVLLEGVASQ PDVPVQRLPL LTEGERTQLL TTWNDTRADF PRDACIHQRF EAQVARTPDA
IAATFEGETL TYRQLDAKAN QLAHHLRRLG VGPEVKVALC LERSLEMVIA VMGVLKAGGA
YVPLDPKYPL DRLSFMLEDT QVPVVLTQDS LADELPVTTQ QLISLDGDWK RSISREREDA
PVTAVTAGNL AYVIYTSGST GRPKGVAIEH RGVSNYLTWC LSAYGLETGA GAPVHSSLAF
DLTVTSMLAP LVAGRGVVMV SETRGVEGLA DVLREGTGFS LVKLTPSHLR LLSDLLGADA
AAGRTGAFVI GGEALFSEEL AFWRKHAPAT RLINEYGPTE TVVGCSVHVV APEDSGSGAV
RIGKPLPNTR MYVLDAQLQP VPVGVPGELY IGGVQVGRGY LGRPELTAEK FIPDAFSTDA
GARLYRSGDL ARWRADGTLE YMGRVDHQVK VRGYRIELGE IESALMGAYG VRESVVVVRE
DVAGDKRLVA YVAGDVESLD RKGLREHLER TLPEYMVPSA FVVMEALPVT SNGKVDRKAL
PVPSDERAQD DAFIAPRTPT EQLLAGAWSE LLNVDRVGST DDFFELGGHS LLATQVLSRV
RSIFRIDLQL RDVFNAPTVQ KLSVLIDQAL QAGAGTQAPA IVPLPREGRL PLSFAQQRLW
FLHQLDASSP AYNVPMVLRL KGSLDVMALE QSFTELVRRH ESLRTSFHLD NGQATQVIHP
AVSLPLPVVD LSDIPEPERH DEARRLADEE AVHPFQLATG PLLRVKLLKL DEEEHILLLV
MHHIVSDGWS MGVLVREMAA SYEAFSNGGT PSLPELPVQY ADYAGWQRGW LQGDVLEKQI
GYWKQQLTGA PSALELPTDR PRPAVQTSHG SSVPVKVSRE LTETLRALAL KEGTTPFMVL
LAAWQTLLSR YSGQDDISVG TPIAGRQRAE TEGLIGFFVN TLVLRTKLDG DPTFRELLGR
VRETTLGAYA HQEVPFEKLV EELAPTRDTS RTPLFQVSMT LQNAPEGSFN LTDLVLEGVE
VEHRTAKFDL SLGLTETANG IEGGLEFNTD LFDASTAERL ARHLGVLLAG IGANPDARLH
QLPLLTEEDR AQVVTDWNTS FRFPVDACLH TLFERQAART PDAVAVTYAE QRLTYRELDT
RANQLAHHLR TLGVGPEVLV GLAVERSLEL MVGLLAILKA GGAYLPMDPA YPRERLEFMV
EDARVPVVLT QQHLLDVVPS GAAKRLCLDS DAAAWASAPG TTPDSGVAPH HLAYVIYTSG
STGRPKGAQI EHAQVVRLFD GTKHWFNFGA KDVWTLFHSY AFDFSVWEMW GALLYGGKLV
VVPYEVSRTP ADFHALLKRE GVTVLNQTPS AFRQLIQHEE RTGDHEGLSL RTVVFGGEAL
EFGSLRPWYA RHADNAPVLV NMYGITETTV HVTYRALKAA DAEGGRGSEV GVAIPDLQVY
VLDAHGQPVP PGVTGEMYVG GEGLSRGYLG RPELTAQRFI PDPFSTRPGA RLYRSGDLAR
WRPDGTLEYL GRADFQVKVR GFRIELGEIE AGLLSHPSVR EAVVLVREDV PGDKRLVAYL
VGAPGQSVAG VPELREQLRR TLPEYMVPSA FMVMDSLPLT SNGKVDRRAL PAPDTTRAEG
STLVVARTPL QLQLVRVWEE TLGMSPIGIR DDFFDLGGHS MLAVQLMGRI QQLTGKNLPL
ASLFQASTVE QLAALLEAGS RAWSPLVALK PEGTKPPLFA IHPAGGGVLC YVDLARELDA
DQPCYGLQAR GTEGEEPLGT VAEMAALYLS AVREVQPHGP YHLAGWSLGG IIAFEMARQL
RAVGEEVALL ASIDAYTVQH MVPDKTPEQV LEDMLTSELT MMLAATTGRD PLELRERISQ
MTQAERVNYF YEVGSQGDTQ IADVGVERVR NLYRVFESTS RAFTQYDAKP LDGKLVLLRA
SQRPDTREHT GWEGLVTGGV EVVDMPGTHM TMMRKPLITN VARELQSRIV THTTPVDDLK
KKIG
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