ID H9F783_MACMU Unreviewed; 500 AA.
AC H9F783;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Cyclin-L2 isoform A {ECO:0000313|EMBL:AFE70492.1};
DE Flags: Fragment;
GN Name=CCNL2 {ECO:0000313|EMBL:AFE70492.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE70492.1};
RN [1] {ECO:0000313|EMBL:AFE70492.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE70492.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin L subfamily.
CC {ECO:0000256|ARBA:ARBA00010589}.
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DR EMBL; JU326736; AFE70492.1; -; mRNA.
DR AlphaFoldDB; H9F783; -.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IEA:UniProt.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20590; CYCLIN_CCNL2_rpt1; 1.
DR CDD; cd20593; CYCLIN_CCNL2_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF45; CYCLIN-L2; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF036580; Cyclin_L; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 2: Evidence at transcript level;
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 63..165
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 174..297
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01332"
FT DOMAIN 178..262
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 299..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE70492.1"
SQ SEQUENCE 500 AA; 56638 MW; 6D894590A00048B9 CRC64;
GAPGSGGAPS GSQGVLIGDR LYSGVLITLE NCLLPDDKLR FTPSMSSGLD TDTETDLRVV
GCELIQAAGI LLRLPQVAMA TGQGLFQRFF YTKSFVKHSM EHVSMACVHL ASKIEEAPRR
IRDVINVFHR LRQLREKKKP VPLLLDQDYV NLKNQIIKAE RRVLKELGFC VHVKHPHKII
VMYLQVLECE RNQHLVQTSW NYMNDSLRTD VFVRFQPESI ACACIYLAAR TLEIPLPNRP
HWFLLFGATE EEIQEICLKI LQLYARKKVD LTHLEGEVEK RKHAIEEAKA QARGLLPGGA
QVLDGTSGFS PAPKLVESPK EGKGSKPSPL SVKNTKRRVE GTKKAKADSP VNGLPKGRES
RSRSRSREQS YSRSPSRSAS PKRRKSDSGS TSGGSKSQSR SRSRSDSPPR QAPRSAPYKG
SEIRGSRKSK DCKYPQKPHK SRSRSSSRSR SRSRERVDNP GKYKKKSHYY RDQRRERSRS
YERTGRRYER DHPGHSRHRR
//
