ID H9FFA3_MACMU Unreviewed; 143 AA.
AC H9FFA3;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Scinderin {ECO:0000256|ARBA:ARBA00014288};
DE AltName: Full=Adseverin {ECO:0000256|ARBA:ARBA00030694};
DE Flags: Fragment;
GN Name=SCIN {ECO:0000313|EMBL:AFE73312.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE73312.1};
RN [1] {ECO:0000313|EMBL:AFE73312.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE73312.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SUBCELLULAR LOCATION: Cell projection, podosome
CC {ECO:0000256|ARBA:ARBA00004188}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the villin/gelsolin family.
CC {ECO:0000256|ARBA:ARBA00008418}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JU329556; AFE73312.1; -; mRNA.
DR AlphaFoldDB; H9FFA3; -.
DR HOGENOM; CLU_002568_3_0_1; -.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd11289; gelsolin_S2_like; 1.
DR Gene3D; 3.40.20.10; Severin; 2.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR007122; Villin/Gelsolin.
DR PANTHER; PTHR11977:SF78; SCINDERIN; 1.
DR PANTHER; PTHR11977; VILLIN; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR PRINTS; PR00597; GELSOLIN.
DR SMART; SM00262; GEL; 1.
DR SUPFAM; SSF55753; Actin depolymerizing proteins; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949}.
FT DOMAIN 50..123
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE73312.1"
FT NON_TER 143
FT /evidence="ECO:0000313|EMBL:AFE73312.1"
SQ SEQUENCE 143 AA; 15870 MW; 79F187B2449E9162 CRC64;
ELQGYESTDF VSYFKDGLKY KAGGVASGLN HVLTNDLTAK RLLHVKGRRV VRATEVPLSW
DSFNKGDCFI IDLGTKIYQW CGSSCNKYER LKANQVATGI RYNERKGRSE LIVVEEGSEP
SELIKVLGGK PELPDGGDDD DII
//
