ID H9FJ02_MACMU Unreviewed; 370 AA.
AC H9FJ02;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Metabotropic glutamate receptor 7 isoform a {ECO:0000313|EMBL:AFE74611.1};
DE Flags: Fragment;
GN Name=GRM7 {ECO:0000313|EMBL:AFE74611.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE74611.1};
RN [1] {ECO:0000313|EMBL:AFE74611.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE74611.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; JU330855; AFE74611.1; -; mRNA.
DR AlphaFoldDB; H9FJ02; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001883; GPCR_3_mGluR7.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF98; METABOTROPIC GLUTAMATE RECEPTOR 7; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR01057; MTABOTROPC7R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AFE74611.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 348..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..246
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
FT DOMAIN 280..331
FT /note="GPCR family 3 nine cysteines"
FT /evidence="ECO:0000259|Pfam:PF07562"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE74611.1"
FT NON_TER 370
FT /evidence="ECO:0000313|EMBL:AFE74611.1"
SQ SEQUENCE 370 AA; 42072 MW; 7D7593DCDBD3A8CC CRC64;
TQISKEAGGL CIAQSVRIPQ ERKDRTIDFD RIIKQLLDTP NSRAVVIFAN DEDIKQILAA
AKRADQVGHF LWVGSDSWGS KINPLHQHED IAEGAITIQP KRATVEGFDA YFTSRTLENN
RRNVWFAEYW EENFNCKLTI SGSKKEDTDR KCTGQERIGK DSNYEQEGKV QFVIDAVYAM
AHALHHMNTD LCADYRGVCP EMEQAGGKKL LKYIRNVNFN GSAGTPVMFN KNGDAPGRYD
IFQYQTTNTS NPGYRLIGQW TDELQLNIED MQWGKGVREI PPSVCTLPCK PGQRKKTQKG
TPCCWTCEPC DGYQYQFDEM TCQHCPYDQR PNENRTGCQD IPIIKLEWHS PWAVIPVFLA
MLGIIATIFV
//
