ID H9FJL5_MACMU Unreviewed; 1687 AA.
AC H9FJL5;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Bromodomain and WD repeat-containing protein 3 {ECO:0000313|EMBL:AFE74824.1};
DE Flags: Fragment;
GN Name=BRWD3 {ECO:0000313|EMBL:AFE74824.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE74824.1};
RN [1] {ECO:0000313|EMBL:AFE74824.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE74824.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
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DR EMBL; JU331068; AFE74824.1; -; mRNA.
DR CDD; cd05529; Bromo_WDR9_I_like; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR16266:SF25; BROMODOMAIN AND WD REPEAT-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR16266; WD REPEAT DOMAIN 9; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF47370; Bromodomain; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 2: Evidence at transcript level;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 162..203
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 204..245
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 246..282
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 344..378
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 447..489
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1144..1214
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1303..1398
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 754..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1248..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1323..1346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1424..1485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1506..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..886
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1324..1346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1439..1454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1462..1485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1507..1521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1522..1536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1552..1589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1590..1612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1613..1634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1635..1649
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1666..1687
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE74824.1"
FT NON_TER 1687
FT /evidence="ECO:0000313|EMBL:AFE74824.1"
SQ SEQUENCE 1687 AA; 190854 MW; AE88713BB5A61B29 CRC64;
LIARFLQSGP CNKSAQVLVQ ELEEHQLIPR RLDWEGKEHR RSFEDLVAAN AHIPPDYLLK
ICERIGPLLD KEIPQSVPGV QTLLGVGRQS LLRDAKDCKS TLWNGSAFAA LHRGRPPELP
VNYVKPPNVV NITSARQLTG CSRFGHIFPS SAYQHIKMHK RILGHLSSVY CVAFDRSGRR
IFTGSDDCLV KIWATDDGRL LATLRGHSAE ISDMAVNYEN TLIAAGSCDK VVRVWCLRTC
APVAVLQGHS ASITSIQFCP STKGTNRYLT STGADGTICF WQWHVKTMKF RDRPVKFTER
SRPGVQISCS SFSSGGMFIT TGSTDHVIRI YYLGSEVPEK IAELESHTDK VVAVQFCNNG
DSLRFVSGSR DGTARIWQYQ QQEWKTIVLD MATKMTGNNL PSGEDKITKL KVTMVAWDRY
DTTVITAVNN FLLKVWNSIT GQLLHTLSGH DDEVFVLEAH PFDQRIILSA GHDGNIFIWD
LDRGTKIRNY FNMIEGQGHG AVFDCKFSPD GNHFACTDSH GHLLLFGFGC SKYYEKIPDQ
MFFHTDYRPL IRDANNYVLD EQTQQAPHLM PPPFLVDVDG NPHPTKFQRL VPGRENCKDE
QLIPQLGYVA NGDGEVVEQV IGQQTNDQDE SILDGIIREL QREQDLRLIN EGDVPHFPVN
RAYSVNGALR SPNMDISSSP NIRLRRHSSQ IEGVRQMHNN APRSQMATER DLMAWSRRVV
VNELNNGVSR VQEECRTAKG DIEISLYTVE KKKKPSYTTQ RNDYEPSCGR SLRRTQRKRQ
HTYQTRSNIE HNSQPSCQNS GVQEDSDSSS EEDETVGTSD ASVEDPVVEW QSESSSSDSS
SEYSDWTADA GINLQPPKRQ TRQTTRKICS SSDEENLKSL EERQKKPKQT RKKKGGLVSM
AGEPNEEWFA PQWILDTIPR RSPFVPQMGD ELIYFRQGHE AYVRAVRKSK IYSVNLQKQP
WNKMDLREQE FVKIVGIKYE VGPPTLCCLK LAFLDPISGK MTGESFSIKY HDMPDVIDFL
VLHQFYNEAK ERNWQIGDRF RSIIDDAWWF GTVESQQPFQ PEYPDSSFQC YSVHWDNNER
EKMSPWDMEP IPEGTAFPDE VGAGVPVSQE ELTALLYKPQ EGEWGAHSRD EECERVIQGI
NHLLSLDFAS PFAVPVDLSA YPLYCTVVAY PTDLNTIRRR LENRFYRRIS ALMWEVRYIE
HNARTFNEPD SPIVKAAKIV TDVLLRFIGD QSCTDILDTY NKIKAEERNS TDAEEDTEMV
DLDSDGPGTS SGRRVKCRGR RQSLKCNPDA WKKQCKELLS LIYEREDSEP FRQPADLLSY
PGYQEQEGES SESVVPERQQ DSSLSEDYQD VIDTPVDFST VKETLEAGNY GSPLEFYKDV
RQIFNNSKAY TSNKKSRIYS MMLRLSALFE SHIKNIISEY KSAIQSQKRR RPRYRKRLRS
SSSSLSSSGA PSPKGKQKQM KLQPKNDQNT SVSYARTSSP FSSPVSDAAE GLSLYLLDDE
PDGPFSSSSF GGYSRSGNSH DPGKAKSLRN RVLPVKQDHS LDGPLTNGDG REPRTGIKRK
LLSASEEDEN MGGEDKEKKE TKEKSHLSTS ESGELGSSLS SESTCGSDSD SESTSRTDQD
YVDGDHDYSK FIQTRPKRKL RKQHGNGKRN WKTRGTGGRG RWGRWGRWSR GGRGRGGRGR
GSRGRGG
//
