ID H9FLV4_MACMU Unreviewed; 153 AA.
AC H9FLV4;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Signal transducer and activator of transcription 6 isoform 2 {ECO:0000313|EMBL:AFE75613.1};
DE Flags: Fragment;
GN Name=STAT6 {ECO:0000313|EMBL:AFE75613.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE75613.1};
RN [1] {ECO:0000313|EMBL:AFE75613.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE75613.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC {ECO:0000256|ARBA:ARBA00005586}.
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DR EMBL; JU331857; AFE75613.1; -; mRNA.
DR AlphaFoldDB; H9FLV4; -.
DR HOGENOM; CLU_014189_2_1_1; -.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR GO; GO:0010033; P:response to organic substance; IEA:UniProt.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001217; STAT.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF48; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 18..133
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE75613.1"
FT NON_TER 153
FT /evidence="ECO:0000313|EMBL:AFE75613.1"
SQ SEQUENCE 153 AA; 17599 MW; 2FA9A146BADE63BE CRC64;
SQFNKEILLG RGFTFWQWFD GVLDLTKRCL RSYWSDRLII GFISKQYVTS LLLNEPDGTF
LLRFSDSEIG GITIAHVIRG QDGSPQIENI QPFSAKDLSI RSLGDRIRDL AQLKNLYPKK
PKDEAFRSHY KPEQMGKDGR GYVPATIKMT VER
//
