ID H9G5Y4_ANOCA Unreviewed; 246 AA.
AC H9G5Y4;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=SGTA homodimerisation domain-containing protein {ECO:0000259|Pfam:PF16546};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002043.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002043.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002043.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002043.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SGT family. {ECO:0000256|ARBA:ARBA00008175}.
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DR AlphaFoldDB; H9G5Y4; -.
DR STRING; 28377.ENSACAP00000002043; -.
DR Ensembl; ENSACAT00000002094.4; ENSACAP00000002043.3; ENSACAG00000002059.4.
DR eggNOG; KOG0553; Eukaryota.
DR GeneTree; ENSGT00940000159037; -.
DR HOGENOM; CLU_044224_0_0_1; -.
DR TreeFam; TF313092; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000002059; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0072380; C:TRC complex; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0006620; P:post-translational protein targeting to endoplasmic reticulum membrane; IBA:GO_Central.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR047150; SGT.
DR InterPro; IPR032374; SGTA_dimer.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45831; LD24721P; 1.
DR PANTHER; PTHR45831:SF3; SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN ALPHA; 1.
DR Pfam; PF16546; SGTA_dimer; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 4..63
FT /note="SGTA homodimerisation"
FT /evidence="ECO:0000259|Pfam:PF16546"
FT REPEAT 90..123
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 124..157
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 158..191
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 65..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 26631 MW; 7F62738DE030F8C8 CRC64;
MGDNKRLAFA IVRFLQDQLQ GGGLSPDAQE SLEVAIQCLE TAFGVSMEDR GLALSQTLPE
IFEAAAAKEP QRDTPTPEPV TPSEEDAAEA ERLKAEGNEQ MKAENFESAV SFYAKAIELN
PANAVYYCNR AAAYSKLGNY AGAVRDCERA IHIDPKYSKA YGRMGLALSS LNKLSEAVVY
YQKALELDPE NETYKSNLKV TEQKMKEAPS PTGGAGGFDL AGLLNNPSFI NMAANLPQPS
LGVLWV
//
