ID H9GA69_ANOCA Unreviewed; 392 AA.
AC H9GA69;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000005311.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000005311.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000005311.4};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000005311.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Musashi family.
CC {ECO:0000256|ARBA:ARBA00006635}.
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DR AlphaFoldDB; H9GA69; -.
DR STRING; 28377.ENSACAP00000005311; -.
DR Ensembl; ENSACAT00000005428.4; ENSACAP00000005311.4; ENSACAG00000005452.4.
DR eggNOG; KOG4205; Eukaryota.
DR GeneTree; ENSGT00940000155420; -.
DR HOGENOM; CLU_012062_3_0_1; -.
DR TreeFam; TF325419; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000005452; Expressed in hindlimb bud and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005844; C:polysome; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0007417; P:central nervous system development; IBA:GO_Central.
DR GO; GO:0006417; P:regulation of translation; IBA:GO_Central.
DR CDD; cd12323; RRM2_MSI; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034126; MSI_RRM2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48032:SF10; RNA-BINDING PROTEIN MUSASHI HOMOLOG 2; 1.
DR PANTHER; PTHR48032; RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 97..174
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 288..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 42054 MW; 794BE95DD98C6B59 CRC64;
MKKKKAGRKL SAPLYFLPLL FLVLTFCFNE KKQNKPKHPL CSCSLSPSRG FGFVTFADPA
SVDKVLAQPH HELDSKTIDP KVAFPRRAQP KMVTRTKKIF VGGLSANTVV EDVKQYFEQF
GKVEDAMLMF DKTTNRHRGF GFVTFENEDV VEKVCEIHFH EINNKMVECK KAQPKEVMFP
PGTRGRARGL PYTMDAFMLG MGMLGYPNFV ATYGRGYPGF APSYSYQFPG FPAAAYGPVA
AAAVAAARGS GIPDYGFYSP PGDLRAPLSY ADYGSMGPRV AQMLRSEHPA SASNSPLHHL
PSPDQFKSPV LNSYSAQPNF GAPASPAGSN PARPGGFPGA NSPGPVADLY GAASQDSGVG
NYISAASPQP GSSFGHGIAS ISGCPGKTGR SF
//
