ID H9J528_BOMMO Unreviewed; 361 AA.
AC H9J528;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DAW {ECO:0000313|EMBL:AKG96796.1};
GN Name=101735420 {ECO:0000313|EnsemblMetazoa:NP_001296564.1};
OS Bombyx mori (Silk moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC Bombycidae; Bombycinae; Bombyx.
OX NCBI_TaxID=7091 {ECO:0000313|EMBL:AKG96796.1};
RN [1] {ECO:0000313|Proteomes:UP000005204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p50T {ECO:0000313|Proteomes:UP000005204};
RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004;
RG International Silkworm Genome Consortium;
RT "The genome of a lepidopteran model insect, the silkworm Bombyx mori.";
RL Insect Biochem. Mol. Biol. 38:1036-1045(2008).
RN [2] {ECO:0000313|EMBL:AKG96796.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Dazao {ECO:0000313|EMBL:AKG96796.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:AKG96796.1};
RA Jiang Y., Gong C.L., Cao G.L., Xue R.Y., Hu X.L.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:NP_001296564.1}
RP IDENTIFICATION.
RC STRAIN=p50T (Dazao) {ECO:0000313|EnsemblMetazoa:NP_001296564.1};
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KP861419; AKG96796.1; -; mRNA.
DR RefSeq; NP_001296564.1; NM_001309635.1.
DR AlphaFoldDB; H9J528; -.
DR SMR; H9J528; -.
DR STRING; 7091.H9J528; -.
DR PaxDb; 7091-BGIBMGA004618-TA; -.
DR EnsemblMetazoa; NM_001309635.1; NP_001296564.1; LOC101735420.
DR GeneID; 101735420; -.
DR KEGG; bmor:101735420; -.
DR eggNOG; KOG3900; Eukaryota.
DR HOGENOM; CLU_664348_0_0_1; -.
DR InParanoid; H9J528; -.
DR OMA; TVVELWF; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000005204; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13752; TGF_beta_INHB; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF294; DAWDLE, ISOFORM A; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000005204};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..361
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010119195"
FT DOMAIN 242..361
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 361 AA; 41348 MW; F2873F726C42EB51 CRC64;
MIAWSTSALV FILVGNFLSL DGEMLGSCAN CANADLSVTQ LTEARIEFVK QQILKKLRMT
KKPAVALPVN SLPMPVAQGQ TLSEGTDKPP EFDDYYGRTE QKIIFPVEGE CLTSGRYPFK
CLQFELPPDV EPEEVSVVEL WFYKERDPFD EYNQTFVISE AAHWDSQQQF KKTKPIAIKE
TDVGEGWVRV ELAWAVRVWL EGRQRLHTLH VACRTCQLRR APLSFHEKHR PFLVLYTKYA
GKRRRGRALE CDPNTNECCR EPLYISFKDL GWDYWIIRPA GYHAYFCKGS CAPISAVTTS
KSYHHDIIRK YFYTVSERVA EFKPCCAPTT FSSLQLLYID STNTVTQKTL PNMVVESCGC
M
//
