ID   H9NC64_9CAUD            Unreviewed;       293 AA.
AC   H9NC64;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   13-SEP-2023, entry version 26.
DE   RecName: Full=glucose-1-phosphate thymidylyltransferase {ECO:0000256|ARBA:ARBA00012461};
DE            EC=2.7.7.24 {ECO:0000256|ARBA:ARBA00012461};
GN   Name=187 {ECO:0000313|EMBL:AFF28185.1};
GN   ORFNames=PAU_187 {ECO:0000313|EMBL:AFF28185.1};
OS   Sphingomonas phage PAU.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX   NCBI_TaxID=1150991 {ECO:0000313|EMBL:AFF28185.1, ECO:0000313|Proteomes:UP000007890};
RN   [1] {ECO:0000313|EMBL:AFF28185.1, ECO:0000313|Proteomes:UP000007890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Pope W.H., Hua J., Hatfull G.F., Hendrix R.W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate +
CC         dTDP-alpha-D-glucose; Xref=Rhea:RHEA:15225, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:37568, ChEBI:CHEBI:57477,
CC         ChEBI:CHEBI:58601; EC=2.7.7.24;
CC         Evidence={ECO:0000256|ARBA:ARBA00001095};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the glucose-1-phosphate thymidylyltransferase
CC       family. {ECO:0000256|ARBA:ARBA00010480}.
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DR   EMBL; JQ362498; AFF28185.1; -; Genomic_DNA.
DR   RefSeq; YP_007006794.1; NC_019521.1.
DR   GeneID; 14012301; -.
DR   KEGG; vg:14012301; -.
DR   OrthoDB; 11040at10239; -.
DR   Proteomes; UP000007890; Genome.
DR   GO; GO:0008879; F:glucose-1-phosphate thymidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR   CDD; cd02538; G1P_TT_short; 1.
DR   InterPro; IPR005907; G1P_thy_trans_s.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR01207; rmlA; 1.
DR   PANTHER; PTHR43532; GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR43532:SF1; GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 1; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007890}.
FT   DOMAIN          7..242
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
SQ   SEQUENCE   293 AA;  32754 MW;  482D9A6C046C9002 CRC64;
     MLTRNRKGII LAGGSGTRLH PLTISVSKQL LPVYDKPMIY YPLTTLIEAG INEILIISTP
     QDRNSFENLL GNGSQFGVRI EYAVQEKPNG LAQAFVIGEE FIGKSKVALI LGDNIFHASN
     IDRLLMEANM SDKNTIFAYR VNDPQRYGVV EFDEYDNAVS IEEKPLNPKS NYAVPGLYFY
     NNDVIEVAKT IKPSARGEYE ISDINAYYLD KNQLSVKAFD RSGTTWLDTG TIQSLAEASL
     FVEVMQNRTG NLIGSPEEAA FRHDEISKDS LIESAKKYDK SGYGEYLLKL VQK
//