ID   H9ZDS0_MACMU            Unreviewed;      1192 AA.
AC   H9ZDS0;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Protein WWC2 {ECO:0000313|EMBL:AFH34086.1};
GN   Name=WWC2 {ECO:0000313|EMBL:AFH34086.1};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|EMBL:AFH34086.1};
RN   [1] {ECO:0000313|EMBL:AFH34086.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Thymus {ECO:0000313|EMBL:AFH34086.1};
RX   PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA   Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA   Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA   Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA   Yorke J.A., Norgren R.B.Jr.;
RT   "A new rhesus macaque assembly and annotation for next-generation
RT   sequencing analyses.";
RL   Biol. Direct 9:20-20(2014).
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DR   EMBL; JU477282; AFH34086.1; -; mRNA.
DR   AlphaFoldDB; H9ZDS0; -.
DR   CDD; cd08680; C2_Kibra; 1.
DR   CDD; cd00201; WW; 2.
DR   Gene3D; 2.20.70.10; -; 2.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR037771; C2_WWC.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR14791; BOMB/KIRA PROTEINS; 1.
DR   PANTHER; PTHR14791:SF26; PROTEIN WWC2; 1.
DR   Pfam; PF00397; WW; 2.
DR   SMART; SM00456; WW; 2.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF51045; WW domain; 2.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS01159; WW_DOMAIN_1; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT   DOMAIN          10..43
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          57..90
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          697..820
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          258..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          873..894
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          911..991
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1124..1143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          305..419
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        262..290
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        873..887
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        949..966
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1124..1141
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1192 AA;  133520 MW;  54E54A805CE44FBC CRC64;
     MPRRAGSGQL PLPRGWEEAR DYDGKVFYID HNTRRTSWID PRDRLTKPLS FADCVGDELP
     WGWEAGFDPQ IGVYYIDHIN KTTQIEDPRK QWRGEQEKML KDYLSVARDA LRTQKELYHV
     KEQRLALALD EYVRLNDAYK EKSSSRTSLF SGSSSSTKYD PDILKAEIST TRLRVKKLKR
     ELSQMKQELL YKEQGFETLQ QIDKKMSGGQ SGYELSEAKA ILTELKSIRK AISSGEKEKQ
     DLMQSLAKLQ ERFHLDQNIG RSEPDLRSSP VSSHLSLSRQ TLDAGSQTSI SGDIGVRSRS
     NLAEKVRLSL QYEEAKRSMA NLKIELSKLD SEAWPGALDV EKEKLMLINE KEELLKELQF
     VTPQKRTQDE LERLEAERQR LEEELLSVRG APSRALAKRL RLEERRKELL QKLEETTRLT
     TYLHSQLKSL SASTLSVSSG SSLGSLASSR GSLNTSSRGS LNSLSSTELY YSSQSDQIDV
     DYQYKLDFLL QEKSGYIPSG PITTIHENEV VKSPSQPGQS GLCGVAAAAT GHTPPLAEAS
     KSVASLSSRS SLSSLSPPGS PLVLEGTFPL SSHDASLHQF SADFEDCELS SHFAGIGLVE
     NQILLDSDSG GASQSLSEDK DLNECAGEPL YEGTADVEKS LPKRRVIHLL GEKTTCVSAA
     VSDESVAGDS GVYEAFVKQP SEIEDVTYSE EDVAIVETAQ VQIGLRYNAK SSSFMVIIAQ
     LRNLHAFLIP HTSKVYFRVA VLPSSTDVSC LFRTKVHPPT ESILFNDVFR VAISQTALQQ
     KTLRVDLCSV SQHRREECLA GTQISLADLP FSSEVFTLWY NLLPSKQMPC KKNEENEDSV
     FQPNQPLGDS IDLDAVSALL ARTSAELLAV EQELAQEEEE EESGQEEQRG PDGDWLTMLR
     EASNEIVAEK EAEVKLPEDS NCTEDLSSCP SVPEVNEDRN RKENNCAKDL RSQPPTGTPT
     LVDKETNTDE AANDNMAVRP KERSSLSSRQ HPFVRSSVIV RSQTFSPGER SQYICRLNRS
     DSDSSTLAKK SLFVRNSTER RSLRVKRTVC QSVLRRTAQE CPVRTSLDLE LDLQASLTRQ
     SRLNDELQAL RDLRQKLEEL KAQGETDLPP GVLEDERFQK LLKQAEKQAE QSKEEQKQGL
     NAEKLMRQVS KDVCRLREQS QKVPRQVQSF REKIAYFTRA KISIPSLPAD DV
//