ID I0BCR4_9BACL Unreviewed; 569 AA.
AC I0BCR4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:AFH60161.1};
GN ORFNames=B2K_05380 {ECO:0000313|EMBL:AFH60161.1};
OS Paenibacillus mucilaginosus K02.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=997761 {ECO:0000313|EMBL:AFH60161.1, ECO:0000313|Proteomes:UP000007392};
RN [1] {ECO:0000313|EMBL:AFH60161.1, ECO:0000313|Proteomes:UP000007392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K02 {ECO:0000313|EMBL:AFH60161.1,
RC ECO:0000313|Proteomes:UP000007392};
RA Xiao B., Sun L., Xiao L., Lian B.;
RT "Complete genome sequence of Paenibacillus mucilaginosus K02.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003422; AFH60161.1; -; Genomic_DNA.
DR AlphaFoldDB; I0BCR4; -.
DR KEGG; pmw:B2K_05380; -.
DR PATRIC; fig|997761.3.peg.1073; -.
DR HOGENOM; CLU_020473_6_2_9; -.
DR Proteomes; UP000007392; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AFH60161.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..357
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 569 AA; 65184 MW; 18CF70D1A8D964DB CRC64;
MKIQPNLSTK MIFAVFMIFL VIFLLYRHTY GINIGVVREE IQRNNLNQLE FFLSQMENQI
DQLAISAYTL ERDPSIQDYR NINHLNHLLD ANKLRITILE KLTLQSASSS WPNQMLLHFP
LTSEIISTAP SLDSDYRGVT GQIHGSWTYI QHGRPEQGEF VFLVAAPQLG RAPVQHPNLV
IETRFQEDNI RKMLDQFKRS GGDPFLFHPQ NGTIANQSSQ AELTNEVTAK LKEQSLSSKG
SQLVLLNHQQ YLVNYVQSKS LGWYLVDYVP LERVLVPIKE GRNFFIVSTV MLLILGIVLS
ALLYRNIQRP ISLFIKVMNK FKQGDLTARV MPIRTYEFRM LYMGFNEMAD RIQELIERVY
LEQIRSQDAV MKQLQSQINP HFLYNCLFFI KSKASVGDME SIKSMALSLG EYYRYLTRVD
TSQTTLGQEL KLVIHYLNIQ NLRKQRIDHV IDIPEPLLEF HIPKLLIQPL VENSIIHGIE
PKVGSGMIRI CAEQSGRWLT IVIEDDGVGM EPEQLQQLRD SLLAPAPKSS GYGLWNVHQR
ILLHFGQGSG LQVSESAAGG IRFTLNIET
//
