ID I0BKL7_9BACL Unreviewed; 608 AA.
AC I0BKL7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B2K_19725 {ECO:0000313|EMBL:AFH62914.1};
OS Paenibacillus mucilaginosus K02.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=997761 {ECO:0000313|EMBL:AFH62914.1, ECO:0000313|Proteomes:UP000007392};
RN [1] {ECO:0000313|EMBL:AFH62914.1, ECO:0000313|Proteomes:UP000007392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K02 {ECO:0000313|EMBL:AFH62914.1,
RC ECO:0000313|Proteomes:UP000007392};
RA Xiao B., Sun L., Xiao L., Lian B.;
RT "Complete genome sequence of Paenibacillus mucilaginosus K02.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003422; AFH62914.1; -; Genomic_DNA.
DR AlphaFoldDB; I0BKL7; -.
DR KEGG; pmw:B2K_19725; -.
DR PATRIC; fig|997761.3.peg.3867; -.
DR HOGENOM; CLU_020473_6_1_9; -.
DR Proteomes; UP000007392; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..363
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 608 AA; 68924 MW; 75EB0025B2649296 CRC64;
MKLQNKLMGG YLLGCAIPVF IVSVIIYNES VAGLEDSSQE FAALYTSQIE HSLDLLMQEY
DKITKTVLVD NDLISGLRDT KQMTMAELIH QREMVRRMLM RVALLKPEIG TVMLIGPDDT
LYHYTNTTSI VNEEALLSQD WYKRLGDSED AFFVTGLHDR AYYEDHGEGA ITTVGRKLFT
YDGAFAGWLL IDLDPFTLLT PNREFVLARD KYDISVVISN GSGEPVYHSD AATGRFTWKD
VLNAGDRYTR EDSGKESIVI SGKVNLGKLK ITTMIPREKL MLRIRKIQTV TAFVILTGFA
IMAIVSIGLN YAITNPIKRL RRSMKQAEAG QYVPIDSAHS RDEIGSLVHS YNKMIITIRT
LIENVYLAEI KQRQAKFLAL QNQINPHMLY NTLESIRMKA LVKDEDEIAY MIKILARMFR
LTLGKEGTLH SIQHELEYTK NYLDLQNIRF DHRFRLHIRL PQDMLACSII PLVFQPIVEN
SIIHGFRDYS HFMNIVIEGS WTEKGGMVIR IIDDGMGMPQ DKQEELSALL EGAASGLHKL
EQTDERSGEG LGLKNIAERI KLHYGDPYDL KFRSERGIGT MVEIHIPSHH TVSGYGRDGA
SYESRTGG
//
