ID I0JHM2_HALH3 Unreviewed; 254 AA.
AC I0JHM2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=GlnR/MerR family transcription regulator Mta {ECO:0000313|EMBL:CCG43640.1};
GN Name=mta {ECO:0000313|EMBL:CCG43640.1};
GN OrderedLocusNames=HBHAL_1263 {ECO:0000313|EMBL:CCG43640.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG43640.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG43640.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
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DR EMBL; HE717023; CCG43640.1; -; Genomic_DNA.
DR RefSeq; WP_014641548.1; NC_017668.1.
DR AlphaFoldDB; I0JHM2; -.
DR STRING; 866895.HBHAL_1263; -.
DR KEGG; hhd:HBHAL_1263; -.
DR PATRIC; fig|866895.3.peg.266; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_6_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000007397};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..70
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 254 AA; 30505 MW; 05E9BFF5B7249257 CRC64;
MYKVKEVARL AGVSIRTLHH YHDIGLLSPS EVKSNGYRYY SEKEITRLQQ ILFFRELDFS
LSKIQEILDA PDFDQEKALH RHKKILLEKS RRLERIILSV EQTLQSLKGG NQMTNHDRFQ
PFDKSQIEQH EKMYEKEVKE RWGETEAYQE SKRRTKAYSE EDWKNIQEEG AEIDKQIIGR
MNQGPDDLDV QRLIDEKRKH ISKYFYDCQL DIFRGLAEMY VSDPRFTKNF DQLQPGYAEF
LRKAMYIYCN RMED
//
