ID I0JJD1_HALH3 Unreviewed; 145 AA.
AC I0JJD1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Mannitol-specific phosphotransferase enzyme IIA component {ECO:0000256|ARBA:ARBA00014783};
DE AltName: Full=EIIA {ECO:0000256|ARBA:ARBA00030956};
DE AltName: Full=EIII {ECO:0000256|ARBA:ARBA00030962};
DE AltName: Full=PTS system mannitol-specific EIIA component {ECO:0000256|ARBA:ARBA00029908};
GN OrderedLocusNames=HBHAL_1887 {ECO:0000313|EMBL:CCG44249.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG44249.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG44249.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (sugar PTS), a major carbohydrate active transport system,
CC catalyzes the phosphorylation of incoming sugar substrates
CC concomitantly with their translocation across the cell membrane. The
CC enzyme II CmtAB PTS system is involved in D-mannitol transport.
CC {ECO:0000256|ARBA:ARBA00002434}.
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DR EMBL; HE717023; CCG44249.1; -; Genomic_DNA.
DR RefSeq; WP_014642153.1; NC_017668.1.
DR AlphaFoldDB; I0JJD1; -.
DR STRING; 866895.HBHAL_1887; -.
DR KEGG; hhd:HBHAL_1887; -.
DR PATRIC; fig|866895.3.peg.887; -.
DR eggNOG; COG4668; Bacteria.
DR HOGENOM; CLU_072531_3_0_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0103111; F:D-glucosamine PTS permease activity; IEA:UniProtKB-EC.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd00211; PTS_IIA_fru; 1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR PANTHER; PTHR30181; MANNITOL PERMEASE IIC COMPONENT; 1.
DR PANTHER; PTHR30181:SF2; PTS SYSTEM MANNITOL-SPECIFIC EIICBA COMPONENT; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
DR PROSITE; PS00372; PTS_EIIA_TYPE_2_HIS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000007397};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000313|EMBL:CCG44249.1};
KW Transport {ECO:0000256|ARBA:ARBA00022597}.
FT DOMAIN 4..144
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 145 AA; 15794 MW; 648FD7080E5E7F2B CRC64;
MSDNILTSNT IELNAQFSSK EEAIRYVGGL LHDGGYVEEA YIDKMMEREE VTSTFMGNYV
AIPHGTEDAK KSVKETGLAV VTVPDGVDFG DGNIVKLLIG IAGKGDEHLQ ILSQIAIVCS
EEENIDTILN AQSKEEIISI FNEVN
//
