ID I0K786_9BACT Unreviewed; 1204 AA.
AC I0K786;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=FAES_1980 {ECO:0000313|EMBL:CCG99989.1};
OS Fibrella aestuarina BUZ 2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrella.
OX NCBI_TaxID=1166018 {ECO:0000313|EMBL:CCG99989.1, ECO:0000313|Proteomes:UP000011058};
RN [1] {ECO:0000313|EMBL:CCG99989.1, ECO:0000313|Proteomes:UP000011058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 2T {ECO:0000313|Proteomes:UP000011058};
RX PubMed=22689241; DOI=10.1128/JB.00550-12;
RA Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine
RT Bacterium.";
RL J. Bacteriol. 194:3555-3555(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; HE796683; CCG99989.1; -; Genomic_DNA.
DR RefSeq; WP_015331088.1; NC_020054.1.
DR AlphaFoldDB; I0K786; -.
DR STRING; 1166018.FAES_1980; -.
DR KEGG; fae:FAES_1980; -.
DR PATRIC; fig|1166018.3.peg.3725; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG5278; Bacteria.
DR HOGENOM; CLU_000445_127_1_10; -.
DR OrthoDB; 9811889at2; -.
DR Proteomes; UP000011058; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd19410; HK9-like_sensor; 1.
DR CDD; cd00156; REC; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR007891; CHASE3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF05227; CHASE3; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 3.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCG99989.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000011058};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..281
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 534..756
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 815..928
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 937..1053
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1083..1200
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 441..517
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 864
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 986
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1133
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1204 AA; 134072 MW; B1EE8E6CC15C7BF6 CRC64;
MPQLANSVIR QLQVVFSLST LLLLISLGAS FYSIRQLIDN SQLVNHTNQV LLESENIISY
MKDAETGQRG YLVTLNRNFL QPYTGSYEKV QNSYEELRAL TRDNDVQQQA LTDIKALYDA
KFAQMRRTIE LTERNPYFGR DTLNRNKEMM RGKQIMDDLR LKINRMKTEE QTLLKRRTEQ
QQTYILFTPY LLVLTAIISI LITLFAYVRI KRDMDVRLAQ QLAAEAEYRR TNHRITVMEG
ITRQIADGHY DVRSTDEQDD ELGRIAKALN GMAASLEQTF TDLKTKNWLQ QGVVRLGEAI
RGEKGLDQLG ARLIDAIASY LKAPLGTLYL TDTDGTFKLA GSYAAQQPPA TVEAGVGLVG
QAIATQKTTV VSGLPADYSP INSSLGSSAP STVVITPLVY DGTCVGAVEL GLLREPTEQE
VHFLEQNSEM MAIGVNATLD FIRLQSLLEE TQTQAEELQM QHSEMENLNA ELEMQAQKLQ
ASEEELRVQQ EELQQTNTEL EERGLLLEER NNDIQKKADE LELATRYKSE FLANMSHELR
TPLNSILLLS RLLAENNEEN LTDDQIEYAK VIQGSGNGLL GLIDEILDLS KIEAGQMKLE
FQDVAVADIT DELQALFGLL AKEKGLDFAI TVAPDVPSLI ETDRMRLGQI LKNLLSNALK
FTSAGRIGLS ISRQAPDAGV LCFSVSDTGI GIPLEKQPLV FEAFQQADGS TKRKYGGTGL
GLSISRELAK LLGGDLTLKS TVGEGSEFTL RLPLTDDVTV APPAPPVQPA FPAPATPPPP
AVEAIPAPSD KRYISPTIPE AIPDDRATIA EGDKVILIIE DDTNFAKSLL DYARRKGYKG
LVSVRGDEGL KLAAQYKPLG ILLDIQLPIM SGWEVMDALK ADPRTRPIPV HIMSSHKLKT
ESRLKGAIDF VDKPMAFEQL QEVFKKIEYV LNRDPKKVLI IEDNPKHAKA LAYFLETFNI
NSELKSNINE GVDALKRNEV DCVILDMGIP DHKAYETLEV AKKNPGLENL PIIIFTGKSL
SMTEELKIKQ YADSIIVKTA HSYQRMLDEV SLFLHLVEEN KQASNNGPTK KLGALTQVLN
GKTVLVADDD VRNIFSLSKA LEQYNMTVIP ALDGKEALQK LRENPGIGIV LLDMMMPQMD
GYETARTIRE QYQWKNLPII AVTAKAMMGD REKCIEAGAS DYITKPVDID QLVSLLRVWL
YDRS
//
