ID I0L622_9ACTN Unreviewed; 1010 AA.
AC I0L622;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Putative transcriptional regulator {ECO:0000313|EMBL:CCH19269.1};
GN ORFNames=MILUP08_44187 {ECO:0000313|EMBL:CCH19269.1};
OS Micromonospora lupini str. Lupac 08.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH19269.1, ECO:0000313|Proteomes:UP000003448};
RN [1] {ECO:0000313|Proteomes:UP000003448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX PubMed=22815450; DOI=10.1128/jb.00628-12;
RA Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA Carro L., Coll P., Trujillo M.E.;
RT "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT Nodules of Lupinus angustifolius.";
RL J. Bacteriol. 194:4135-4135(2012).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH19269.1}.
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DR EMBL; CAIE01000032; CCH19269.1; -; Genomic_DNA.
DR AlphaFoldDB; I0L622; -.
DR STRING; 1150864.MILUP08_44187; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR OrthoDB; 33864at2; -.
DR Proteomes; UP000003448; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000003448}.
FT DOMAIN 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1010 AA; 108636 MW; B3EDDACBDCDA42B2 CRC64;
MQFGVLGPLA VTTDAGEPVA VPGTKVRALL ADLLTNRNQV VSADRLIDDL WGDDSPANPA
GALQVRVSQL RKALNDAEPG ARDLVESRAP GYLLRAGAVD ADRFAELARH TDVDRLTEAL
GLWRGEAYAD VADAEFVRAE ATRLAEQRLA VHERLAEARV ARGEHDLVAA DLAELVARHP
LREGLRAVQL RALYAAGRQS EALDSYADLR DRLADELGLD PAPELVALHR RILEQDAGLS
APPKAAIIRN SLPAQLDELV GRGEALTELR ALLPAQRLVT LIGPGGVGKT RLATETARTQ
SLPDGVLLVE LAPLPAGDPG VAEQVLGALD AREAAGTTLS ATDRLVAALR QRHLLLVLDN
CEHVIEPVAA LVARLLRDAP GVRVLATSRE SLGLTGELLW EVPPLSLPQD SDPDAVRRSA
AARLFAARAA AQHRGFRLDE TTAPAVAQLC RRLDGLPLAL ELAATRVRAL GLRGVVDRLD
DRFRLLTTSQ RDVPRRQRTL TAVIGWSWDL LDEADREVLA RLAVFRDGCT PEAAEQVCQA
DLDALARLVD RSLVVLDDSP AGPRYRLLES VAAFCLDRLT DADDVRARHA AYYTDLAERA
DPELRGAEQR RWLALLDAET ANLRAALAHG GGLRLAVALS WYWYLRGRLT EARRALAVPG
DPAQESRAAP WQVGFALLRG EAVTPADIRA ALAHDPDGRG AWFAAHAVIT HSELALAAEL
LPSAPADAWT EAAVLASRAM LAHAAGDQST LEYASTRSAA LFADLGDRWG RLQATEWVGG
LAEMRGEHER AVELHREGLR WAEELELWPQ VGTELSWLAW LAVQTRDYPQ GRELAERAYR
LAVEQDAPGA LVFAGMSLGF AARRDGKLDL AVTHLTHLAE RGRGETRPAL YLPMVLVELG
YAVEQGGDPD AALALHVEAY EAAEAMASPR DGVAALEGMA SAVRSPEAAA RLLGVAAAAR
LALEAPASPA ERDEVDRVTG RVRAALGPER FDALVDEGTK LSPGEARAQL
//
