ID I0QKT3_STRSL Unreviewed; 694 AA.
AC I0QKT3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=ATP-dependent Clp protease, ATP-binding subunit {ECO:0000313|EMBL:EIC81893.1};
GN ORFNames=PS4_86127 {ECO:0000313|EMBL:EIC81893.1};
OS Streptococcus salivarius PS4.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1157946 {ECO:0000313|EMBL:EIC81893.1, ECO:0000313|Proteomes:UP000010314};
RN [1] {ECO:0000313|EMBL:EIC81893.1, ECO:0000313|Proteomes:UP000010314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS4 {ECO:0000313|EMBL:EIC81893.1,
RC ECO:0000313|Proteomes:UP000010314};
RX PubMed=22843595; DOI=10.1128/JB.00896-12;
RA Martin V., Maldonado-Barragan A., Jimenez E., Ruas-Madiedo P.,
RA Fernandez L., Rodriguez J.M.;
RT "Complete Genome Sequence of Streptococcus salivarius PS4, a Strain
RT Isolated from Human Milk.";
RL J. Bacteriol. 194:4466-4467(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC81893.1}.
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DR EMBL; AJFW01000004; EIC81893.1; -; Genomic_DNA.
DR AlphaFoldDB; I0QKT3; -.
DR PATRIC; fig|1157946.4.peg.29; -.
DR Proteomes; UP000010314; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EIC81893.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:EIC81893.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:EIC81893.1}.
FT DOMAIN 104..251
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 435..587
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 601..688
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 318..364
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 694 AA; 76545 MW; B8B5E80446FBE3DF CRC64;
MDDLFNQLMG NMGGYRSENR RYMINGREVT PEEFAIYRQT GQLPANEGEA VNPTQQQGKG
PKQDGILAKL GRNLTEEARE GKLDPVIGRN KEIQEACEIL ARRTKNNPVL VGDAGVGKTA
VVEGLAQAIV NGDVPAAIKN KEIISIDISG LEAGTQYRGS FEENIQNLVN EVKEAGNIIL
FFDEIHQILG AGSTGDGQGS KGLADILKPA LSRGELTVIG ATTQDEYRNT ILKNAALARR
FNEVKVNAPS AEDTFKILQG IRDLYEKHHN VILPDDVLKA AVDFSVQYIP QRSLPDKAID
LVDVTAAHLA AQHPVTDVNA VEREIEEEKA KQEAAAAKED YEAALNAKVR IEKLEKKIAN
HAEDHKVTAT VNDVAESVER MTGIPVSQMG ATDIERLKDM GNRLQTKVIG QDKAVEAVAR
AIRRNRAGFD EGNRPIGSFL FVGPTGVGKT ELAKQLALDM FGTKDAIIRL DMSEYSDRTA
VSKLIGTTAG YVGYDDNSNT LTERVRRNPY SIILLDEIEK ADPQVITLLL QVLDDGRLTD
GQGNTVNFKN TVIIATSNAG FGYEANLTED AEKPELLDRL KPYFRPEFLN RFNAVIEFSH
LSKENLSKIV DLMLVDVNKT LSKKEIDLAV SEAAKEYMTE EGYDEVMGVR PLRRVVEQQI
RDKVTDFHLD NLDAKHLEAD MEDGVLVIKE KDAK
//
