ID   I0XN71_9LEPT            Unreviewed;       384 AA.
AC   I0XN71;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Cobalamin biosynthesis protein {ECO:0000313|EMBL:EIE00329.1};
GN   ORFNames=LEP1GSC185_3346 {ECO:0000313|EMBL:EIE00329.1};
OS   Leptospira licerasiae serovar Varillal str. VAR 010.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1049972 {ECO:0000313|EMBL:EIE00329.1, ECO:0000313|Proteomes:UP000004889};
RN   [1] {ECO:0000313|EMBL:EIE00329.1, ECO:0000313|Proteomes:UP000004889}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VAR 010 {ECO:0000313|EMBL:EIE00329.1};
RX   PubMed=23145189; DOI=10.1371/journal.pntd.0001853;
RA   Ricaldi J.N., Fouts D.E., Selengut J.D., Harkins D.M., Patra K.P.,
RA   Moreno A., Lehmann J.S., Purushe J., Sanka R., Torres M., Webster N.J.,
RA   Vinetz J.M., Matthias M.A.;
RT   "Whole Genome Analysis of Leptospira licerasiae Provides Insight into
RT   Leptospiral Evolution and Pathogenicity.";
RL   PLoS Negl. Trop. Dis. 6:E1853-E1853(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIE00329.1}.
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DR   EMBL; AHOO02000012; EIE00329.1; -; Genomic_DNA.
DR   RefSeq; WP_008590336.1; NZ_AHOO02000012.1.
DR   AlphaFoldDB; I0XN71; -.
DR   PATRIC; fig|1049972.3.peg.3169; -.
DR   OrthoDB; 9781023at2; -.
DR   Proteomes; UP000004889; Unassembled WGS sequence.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.11220; -; 1.
DR   Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR   InterPro; IPR021745; CbiG_mid.
DR   InterPro; IPR021744; CbiG_N.
DR   InterPro; IPR002750; CobE/GbiG_C.
DR   InterPro; IPR036518; CobE/GbiG_C_sf.
DR   InterPro; IPR038029; GbiG_N_sf.
DR   PANTHER; PTHR37477; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR   PANTHER; PTHR37477:SF1; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR   Pfam; PF01890; CbiG_C; 1.
DR   Pfam; PF11761; CbiG_mid; 1.
DR   Pfam; PF11760; CbiG_N; 1.
DR   SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR   SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          57..137
FT                   /note="Cobalamin synthesis G N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11760"
FT   DOMAIN          144..239
FT                   /note="Cobalamin biosynthesis central region"
FT                   /evidence="ECO:0000259|Pfam:PF11761"
FT   DOMAIN          242..366
FT                   /note="CobE/GbiG C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01890"
SQ   SEQUENCE   384 AA;  42332 MW;  D26AE4A27F33803A CRC64;
     MILSRKPYAI YVITKHGLKT GIELLYSIGE AELFVSPKFI SEAPEGSKLL NLPMEPTLRE
     TFTEYDCHIF VISVGAVVRM ISPLLVSKKT DPAVLCIDDQ AKFTVCLLSG HVGRGNFFTQ
     RISDLLGNIP VITTASDVSG TLTVDILGRE LGWSLDDHDR NVTKACAAVV NETKVLFVQE
     TGEPNFWPLE KDLPKGVEYS LNLENVVPEN YEIILIASDR TDIKTKTPEV YSNSVIYRPK
     SLILGLGCDK GIPIEVVENG ILKVLKEYDL SLESVKGIAS VDAKKEEPAF LEISQKYGWE
     FITFSPEKLD HVEGISEISK AASEYVGTRS VSEAAALLLS GSDRLLVTKQ KYKETEGGKN
     LTVAIARIQF AARPQIYSAN LEKV
//