ID I0XPP5_9LEPT Unreviewed; 755 AA.
AC I0XPP5;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Pyridine nucleotide-disulfide oxidoreductase / 4Fe-4S binding domain multi-domain protein {ECO:0000313|EMBL:EIE00853.1};
GN ORFNames=LEP1GSC185_0511 {ECO:0000313|EMBL:EIE00853.1};
OS Leptospira licerasiae serovar Varillal str. VAR 010.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049972 {ECO:0000313|EMBL:EIE00853.1, ECO:0000313|Proteomes:UP000004889};
RN [1] {ECO:0000313|EMBL:EIE00853.1, ECO:0000313|Proteomes:UP000004889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VAR 010 {ECO:0000313|EMBL:EIE00853.1};
RX PubMed=23145189; DOI=10.1371/journal.pntd.0001853;
RA Ricaldi J.N., Fouts D.E., Selengut J.D., Harkins D.M., Patra K.P.,
RA Moreno A., Lehmann J.S., Purushe J., Sanka R., Torres M., Webster N.J.,
RA Vinetz J.M., Matthias M.A.;
RT "Whole Genome Analysis of Leptospira licerasiae Provides Insight into
RT Leptospiral Evolution and Pathogenicity.";
RL PLoS Negl. Trop. Dis. 6:E1853-E1853(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE00853.1}.
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DR EMBL; AHOO02000011; EIE00853.1; -; Genomic_DNA.
DR RefSeq; WP_008595843.1; NZ_AHOO02000011.1.
DR AlphaFoldDB; I0XPP5; -.
DR PATRIC; fig|1049972.3.peg.3000; -.
DR OrthoDB; 9778740at2; -.
DR Proteomes; UP000004889; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR48105:SF33; OXIDOREDUCTASE; 1.
DR PANTHER; PTHR48105; THIOREDOXIN REDUCTASE 1-RELATED-RELATED; 1.
DR Pfam; PF12801; Fer4_5; 2.
DR Pfam; PF13187; Fer4_9; 1.
DR Pfam; PF13738; Pyr_redox_3; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 681..710
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 712..741
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 755 AA; 84258 MW; BDB7C2E1B07371C8 CRC64;
MSLLSFVPKY FDWLNNDAPQ GESEKYPETN SEFESSIPGI YISGDLTGVP LLKYSVKSGV
SVIQSILRKP KKKTKGNLDV LIIGAGPSGI AAGIEAKKNG LDFLILEANQ PFHTITSYPK
GKPIFAEPSE LKVDSPIQIK DTTKEDLLKS LEKVLKKHKL PILNGEKVEM IQPSRGSEQG
FEIRTESGKQ FHTTYVVLAI GKSGDSRRLG IPGEEQENVF HRLIDPQDFR GQNTLVIGGG
DSAIEAALSL VDVSSSVTLS YRESEISRPK EENKRKFEKA IKENKIRFVP NSTLQKFGSK
QVLIKQGSKT RTEKIDSSLV LIGSEPPLSF LERIGIKIRN SLNSKEVIGF VSLFSFALFL
YFGKASFYAS FWYSWVALGS GIVFALSSVR FLFSKGTFSS LRWRTFKNLY LLSAALYFSA
VYLSAKYLGF YLFGKYPNFH YTVLYSATIL FFGIRRIQVR PTQYIKLQTI TLILIQIFPL
FLLPEIILPF LGDKGILGPS NGFLLTQVFP DGAYWKAYGF ILAWPLNMGV LYDGGITTFW
LIYGFLMSFG LIPYLVYKFG KGAYCGWICS CGGLAETLGD EYRNRMPHGK LAYKLEHSGQ
WILLIAAILT VAKLIGSSGQ FFWPLEFGAD SVKVYYDLIV DLGLGGVVGV GAYFMFSGRI
WCRMFCPLSA LMHIYAKFSK FRIFSEKKRC ISCNICTSVC HQGIDVMNYA NKGRPMDSVQ
CVRCSACVVN CPTQVLSFGK LEKSGQVLDT LKAVL
//
