ID I0YRM3_COCSC Unreviewed; 586 AA.
AC I0YRM3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSUDRAFT_30231 {ECO:0000313|EMBL:EIE21042.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE21042.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE21042.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE21042.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE21042.1}.
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DR EMBL; AGSI01000013; EIE21042.1; -; Genomic_DNA.
DR RefSeq; XP_005645586.1; XM_005645529.1.
DR AlphaFoldDB; I0YRM3; -.
DR STRING; 574566.I0YRM3; -.
DR GeneID; 17039024; -.
DR KEGG; csl:COCSUDRAFT_30231; -.
DR eggNOG; ENOG502QQ5E; Eukaryota.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 120..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 586 AA; 62414 MW; 0B985E59904B8CC3 CRC64;
MGIREAWNAC WDHANDHIGK SAVGRYFQLE ERRSTFTQEL RAGTVTFLTT AYILAVNALI
LSDTGGPCSA DDCTGPEKGN QDCVYPDDYG VTNIGYMTCV AGVRQSLVTA TAASSCIASL
LMGIGANLPV ALAPGMGLNA YFAYNVVGYR GSGKVSYQTA LAAVFVEGWI FIILAVTGLR
LRLIRLVPKS IMLATSAGIG LFLAFIGLQS TEGLGVISYD PATLVSLGGC PALKHEYAYV
IDNPLTVCSV TNGVPVTNLP PPSSNYACVG DKMESGSMWL GIAGLMIIGI LMSRSFKGSI
VIGIAFVTVI AWIPGHAASY FGKASTIPGG QERLQYFKNV VDLPTLKSTG MAISFAGFTS
GELWIALVTF LYVDFLDTTG TLFSMANFIN NYVPGFVNEK KEFPRQMMAF CMDGIGSIIG
SLMGTSPIAA FIESASGIRE GGRTGLTAVC VSAWFFVALF FTPVLSNVPP YAIGPALITV
GALMMMNVVR IRWEQSAEAL PAFITIILMP LTYSIAYGII GGLLAYMIIH SANWIIDKVS
EFGHWTMTGT DTDVPVIVDR SFIGRVASNT GTAGLVRSPA EIVNFL
//
