ID I0Z5N4_COCSC Unreviewed; 701 AA.
AC I0Z5N4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=COCSUDRAFT_13147 {ECO:0000313|EMBL:EIE25953.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE25953.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE25953.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE25953.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE25953.1}.
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DR EMBL; AGSI01000003; EIE25953.1; -; Genomic_DNA.
DR RefSeq; XP_005650497.1; XM_005650440.1.
DR AlphaFoldDB; I0Z5N4; -.
DR STRING; 574566.I0Z5N4; -.
DR GeneID; 17043957; -.
DR KEGG; csl:COCSUDRAFT_13147; -.
DR eggNOG; KOG0922; Eukaryota.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF234; ATP-DEPENDENT RNA HELICASE DHX40-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EIE25953.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT DOMAIN 16..180
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 203..387
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 701 AA; 77599 MW; 9F79166DE9A2E81B CRC64;
MTAKELPIWP FRQTILDTVF KHPITVIIGE TGSGKTTQIA QMLDKAYCAR EGCIGVTQPR
RVAALTVARR VAEEMRCEVG QEVGYRVRFE ERTSRRTRIV YLTDGTLLRE MLDDPELSAY
SVIVLDEAHE RSLNTDVLFG VLKSLVKTRQ KPLKLILTSA TLDSAKFSAY FDGCPVLNIP
GRQYEVQIVH SQGNHENDYL AAAVDTALDI HLHQPPGDIL VFLTGQAEID KAVKQLSEAI
AELPEDSCPD LLILPLYAAM PLELQARVFA PPPDGCRRLI MATNIAETSI TVDGVVYVVD
PGMVKQKSYT PATGMESLHV VPISRVQATQ RAGRAGRVCN GKCYRLYTAQ FFEREMSETT
VPEIQRTNML TAVLYLKSLP LDIDVLAFDY LDSPGSEALE DALRQLLILD ALDRDGHITE
LGRRMAALPL EPSLARSLLA AADHDCLPET LTAAAMLSAE TIFLGNRQGE LSEQGRAALA
ELMKEGLGDH ILMLRIFQAW ERNSFSSKWC KDMGLDVRGM HFAREVRKQL ADLGSCKSQA
RGGLCLAGVD ALRRALLVGF ANRLARRMPR HNGYKTLNER ATLAQLHPAT ARIAADEDGL
MPEFVIYYAL FATAKVFLSK VCPMDSEWVE DILPKLRNID VERLSGGMTT KKAAKRAAVV
GDLSEKQVVK NVPVANARKN DLAAVDAARQ RYLARKSDKK K
//
