ID I1CYT0_9PSEU Unreviewed; 468 AA.
AC I1CYT0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=FAD/FMN-dependent dehydrogenase {ECO:0000313|EMBL:EIE97854.1};
GN ORFNames=SacglDRAFT_00916 {ECO:0000313|EMBL:EIE97854.1};
OS Saccharomonospora glauca K62.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=928724 {ECO:0000313|EMBL:EIE97854.1, ECO:0000313|Proteomes:UP000005087};
RN [1] {ECO:0000313|EMBL:EIE97854.1, ECO:0000313|Proteomes:UP000005087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K62 {ECO:0000313|EMBL:EIE97854.1,
RC ECO:0000313|Proteomes:UP000005087};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Brambilla E., Klenk H.-P., Woyke T.J.;
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K62 {ECO:0000313|Proteomes:UP000005087};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Held B., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Brambilla E.-M.,
RA Klenk H.-P., Woyke T.;
RT "Noncontiguous Finished sequence of chromosome of Saccharomonospora glauca
RT K62.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CM001484; EIE97854.1; -; Genomic_DNA.
DR RefSeq; WP_005462085.1; NZ_CM001484.1.
DR AlphaFoldDB; I1CYT0; -.
DR STRING; 928724.SacglDRAFT_00916; -.
DR eggNOG; COG0277; Bacteria.
DR HOGENOM; CLU_048432_0_0_11; -.
DR OrthoDB; 5482059at2; -.
DR Proteomes; UP000005087; Chromosome.
DR GO; GO:0050614; F:delta24-sterol reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.40.462.10; FAD-linked oxidases, C-terminal domain; 1.
DR InterPro; IPR016170; Cytok_DH_C_sf.
DR InterPro; IPR040165; Diminuto-like.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR10801; 24-DEHYDROCHOLESTEROL REDUCTASE; 1.
DR PANTHER; PTHR10801:SF0; DELTA(24)-STEROL REDUCTASE; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005087}.
FT DOMAIN 14..188
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 54055 MW; DC57B6F53F766047 CRC64;
MVLDNRSASY PEPGTSRSLS VVPGHPERVE ALRAQFAEQP PDLPVRLAKR TSNLFRSRSR
RDTPGLDVSE LTHVLHVDPV ARTADVEGMV TYEQLVDATL PYGLMPMVVP QLKTITIGGA
ITGLGIESSS FRNGMPHESV LELEILTGSG EVVVARPDNE HAELFFGFPN SYGTLGYALR
ARIELEPVRP YVRLRHLRHT DPRSYFAELA RVCAEGTADF VDGTVFGPDE LYLTLGTFTD
EAPKLSDYTW LDIYYRSIRE RDIDYLHTRD YLWRWDTDWF WCSRALGVQH RPVRLLLGPQ
RLRSDVYWKV VAFDRRYDLS NRVNRLLGRP RREPVVQDVE IPVDAAPEFL DFLHRDIRIS
PVWICPVRQR HPDRQWPLYE LDPHTLYVNF GFWGTVPVRK DAPRGEHNRA VEAKVTELGG
RKSLYSEAFY DERTFWRLYN GTAYARLKHR YDPRGRLLDL YAKCVKSE
//
