ID I1H5P4_BRADI Unreviewed; 494 AA.
AC I1H5P4;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=fumarate hydratase {ECO:0000256|ARBA:ARBA00012921};
DE EC=4.2.1.2 {ECO:0000256|ARBA:ARBA00012921};
GN Name=100821540 {ECO:0000313|EnsemblPlants:KQK21775};
GN ORFNames=BRADI_1g63020v3 {ECO:0000313|EMBL:KQK21775.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK21775.1};
RN [1] {ECO:0000313|EMBL:KQK21775.1, ECO:0000313|EnsemblPlants:KQK21775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK21775.1,
RC ECO:0000313|EnsemblPlants:KQK21775};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK21775.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK21775.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK21775}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK21775};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class-II fumarase/aspartase family. Fumarase
CC subfamily. {ECO:0000256|ARBA:ARBA00009084}.
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DR EMBL; CM000880; KQK21775.1; -; Genomic_DNA.
DR EMBL; CM000880; PNT77454.1; -; Genomic_DNA.
DR RefSeq; XP_003557953.1; XM_003557905.3.
DR AlphaFoldDB; I1H5P4; -.
DR STRING; 15368.I1H5P4; -.
DR EnsemblPlants; KQK21775; KQK21775; BRADI_1g63020v3.
DR EnsemblPlants; PNT77454; PNT77454; BRADI_1g63020v3.
DR GeneID; 100821540; -.
DR Gramene; KQK21775; KQK21775; BRADI_1g63020v3.
DR Gramene; PNT77454; PNT77454; BRADI_1g63020v3.
DR KEGG; bdi:100821540; -.
DR eggNOG; KOG1317; Eukaryota.
DR HOGENOM; CLU_021594_4_1_1; -.
DR InParanoid; I1H5P4; -.
DR OMA; AKWRAQT; -.
DR OrthoDB; 1341425at2759; -.
DR Proteomes; UP000008810; Chromosome 1.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
DR GO; GO:0004333; F:fumarate hydratase activity; IBA:GO_Central.
DR GO; GO:0006106; P:fumarate metabolic process; IBA:GO_Central.
DR GO; GO:0006108; P:malate metabolic process; IBA:GO_Central.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IBA:GO_Central.
DR CDD; cd01362; Fumarase_classII; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR HAMAP; MF_00743; FumaraseC; 1.
DR InterPro; IPR005677; Fum_hydII.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR018951; Fumarase_C_C.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR NCBIfam; TIGR00979; fumC_II; 1.
DR PANTHER; PTHR11444; ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE; 1.
DR PANTHER; PTHR11444:SF1; FUMARATE HYDRATASE, MITOCHONDRIAL; 1.
DR Pfam; PF10415; FumaraseC_C; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 42..372
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 438..490
FT /note="Fumarase C C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10415"
SQ SEQUENCE 494 AA; 53171 MW; ED6653541D7121DE CRC64;
MAMVLRRLAG ASGSPSAAAL LFRPALTRPI STGFREERDT FGPIRVPSDK LWGAQTQRSL
QNFDIGGERE RMPVPIIRAF GVLKKCAAKV NMEYGLDPTI GKAIMQAAEE VAEGKLDDHF
PLVIWQTGSG TQSNMNANEV IANRAAEILG HKRGDKFVHP NDHVNRSQSS NDTFPTVMHI
AAAVEINSRF IPSLEQLHKS LHSKSDEFKD IIKIGRTHTQ DATPLTLGQE FSGYATQVKY
GIDRIACTLP RMYQLAQGGT AVGTGLNTKK GFDCKIAAAV AEETDLPFVT AENKFEALAA
HDAFVESSGA VNTISASLMK IANDIRLLGS GPRCGLGELS LPENEPGSSI MPGKVNPTQC
EALTMVCAQV MGNHVGVTIG GSNGHFELNV FKPMIAAGLL RSLRLLGDAS VSFEKNCVRG
IEANHKRISQ LLHESLMLVT SLNPKIGYDN AAAVAKKAHK EGTTLKEAAL SLGVLTEKEF
HELVVPEKMI GPSD
//
