ID I1HBH8_BRADI Unreviewed; 336 AA.
AC I1HBH8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Protein-lysine N-methyltransferase BRADI_2g01570v3 {ECO:0000256|HAMAP-Rule:MF_03188};
DE EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03188};
GN Name=100825409 {ECO:0000313|EnsemblPlants:KQK02459};
GN ORFNames=BRADI_2g01570v3 {ECO:0000313|EMBL:KQK02459.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK02459.1};
RN [1] {ECO:0000313|EMBL:KQK02459.1, ECO:0000313|EnsemblPlants:KQK02459}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK02459.1,
RC ECO:0000313|EnsemblPlants:KQK02459};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK02459.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK02459.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK02459}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK02459};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC methyltransferase that methylates elongation factor 1-alpha.
CC {ECO:0000256|HAMAP-Rule:MF_03188}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03188}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EFM4 family. {ECO:0000256|HAMAP-Rule:MF_03188}.
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DR EMBL; CM000881; KQK02459.1; -; Genomic_DNA.
DR RefSeq; XP_003567737.1; XM_003567689.3.
DR AlphaFoldDB; I1HBH8; -.
DR STRING; 15368.I1HBH8; -.
DR EnsemblPlants; KQK02459; KQK02459; BRADI_2g01570v3.
DR GeneID; 100825409; -.
DR Gramene; KQK02459; KQK02459; BRADI_2g01570v3.
DR KEGG; bdi:100825409; -.
DR eggNOG; KOG1271; Eukaryota.
DR HOGENOM; CLU_044783_0_1_1; -.
DR InParanoid; I1HBH8; -.
DR OMA; QERSHAD; -.
DR OrthoDB; 390334at2759; -.
DR Proteomes; UP000008810; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_03188; Methyltr_EFM4; 1.
DR InterPro; IPR026635; Efm4/METTL10.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12843; PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10; 1.
DR PANTHER; PTHR12843:SF6; PROTEIN-LYSINE N-METHYLTRANSFERASE OS01G0121100; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03188};
KW Methyltransferase {ECO:0000256|HAMAP-Rule:MF_03188};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_03188};
KW Transferase {ECO:0000256|HAMAP-Rule:MF_03188}.
FT DOMAIN 165..292
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
SQ SEQUENCE 336 AA; 36210 MW; AA4E2E32BB51F459 CRC64;
MAGIRWPPED PEMFPTRMLG SGVWAGAGAG APGEMASDDD RSVAADSWSI KSDYGSTLDD
EQRYADTAEV LLASSCSASS ASSSVVAPSS ASSLSAHHSS DFSFDKDVPD VVPPMLGLHN
YHDGAYAEDL AHYHERSHAD DWFGTEVMDV LVGWTTNLCS SKNLPGCSVL DIGTGSGRLL
QQLAKQGFSD LTGIDYSEAA IEHARNLSIR DGFEHINFLV DDVLESKLER RFELVMDEGT
LDAIGLHPDG PVKRMMYWQS VASLVSPGGV LVITSCSRTK DELVQEVENF NQRKLGATVS
EGALGSDAVV FKYLDHVQAY PNVDSPCIAT VAFLHM
//
