ID I1ITV1_BRADI Unreviewed; 444 AA.
AC I1ITV1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN Name=100845854 {ECO:0000313|EnsemblPlants:KQJ91981};
GN ORFNames=BRADI_4g40960v3 {ECO:0000313|EMBL:KQJ91981.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ91981.1};
RN [1] {ECO:0000313|EMBL:KQJ91981.1, ECO:0000313|EnsemblPlants:KQJ91981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ91981.1,
RC ECO:0000313|EnsemblPlants:KQJ91981};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ91981.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ91981.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ91981}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ91981};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CM000883; KQJ91981.1; -; Genomic_DNA.
DR RefSeq; XP_003578822.1; XM_003578774.3.
DR AlphaFoldDB; I1ITV1; -.
DR STRING; 15368.I1ITV1; -.
DR EnsemblPlants; KQJ91981; KQJ91981; BRADI_4g40960v3.
DR GeneID; 100845854; -.
DR Gramene; KQJ91981; KQJ91981; BRADI_4g40960v3.
DR KEGG; bdi:100845854; -.
DR eggNOG; KOG1343; Eukaryota.
DR HOGENOM; CLU_007727_8_2_1; -.
DR InParanoid; I1ITV1; -.
DR OMA; CTSPAMG; -.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; I1ITV1; baseline and differential.
DR GO; GO:0009570; C:chloroplast stroma; IEA:EnsemblPlants.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblPlants.
DR GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblPlants.
DR GO; GO:0043014; F:alpha-tubulin binding; IEA:EnsemblPlants.
DR GO; GO:0048487; F:beta-tubulin binding; IEA:EnsemblPlants.
DR GO; GO:0004407; F:histone deacetylase activity; IBA:GO_Central.
DR GO; GO:0051721; F:protein phosphatase 2A binding; IEA:EnsemblPlants.
DR GO; GO:0043621; F:protein self-association; IEA:EnsemblPlants.
DR GO; GO:0042903; F:tubulin deacetylase activity; IEA:EnsemblPlants.
DR GO; GO:0030186; P:melatonin metabolic process; IEA:EnsemblPlants.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0042548; P:regulation of photosynthesis, light reaction; IEA:EnsemblPlants.
DR CDD; cd09992; HDAC_classII; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 101..405
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 444 AA; 48018 MW; 941F070B6A0D9343 CRC64;
MMERLWIPSH QTLGGRMLPF LRHYCVFGSH HPLTWSGLQT TERKHNQNGG WIAQCAASGN
GPSVSDINGA QKDFALPDSL LCNARILYCA SPAMGHNKES HPESNKRVPA IVDALEKLEL
TPKHRGSQVL EIQNFHPASL DDVARVHSRK YITGLEKAMS RASDEGLIFI EGTGPTYATQ
TTFQESLLAA GAGITLVDSV VAASKLGPSP PLGFALVRPP GHHAVPEGPM GFCVFGNIAV
AARYAQHQHG LKRVMIIDFD VHHGNGTCDA FYDDPDIFFL STHQLGSYPG TGKMNLIGQG
SSEGTTLNLP LPGGSGDYSM RCAFDEVIAP SAQRFKPDII LVSAGYDAHA LDPLAGLQFT
TGTYYTLASS IKQLAGDLCG GRCVFFLEGG YNLQSLSSSV ADTFRAFLDE PSLAAQFDNP
AMLYEEPTRR VKEAIEKVRH LHSL
//
