ID I1J2K8_BRADI Unreviewed; 550 AA.
AC I1J2K8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=BRCA1-associated protein {ECO:0008006|Google:ProtNLM};
GN Name=100833841 {ECO:0000313|EnsemblPlants:KQJ84968};
GN ORFNames=BRADI_5g23970v3 {ECO:0000313|EMBL:KQJ84968.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ84968.1};
RN [1] {ECO:0000313|EMBL:KQJ84968.1, ECO:0000313|EnsemblPlants:KQJ84968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ84968.1,
RC ECO:0000313|EnsemblPlants:KQJ84968};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ84968.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ84968.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ84968}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ84968};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; CM000884; KQJ84968.1; -; Genomic_DNA.
DR RefSeq; XP_010240522.1; XM_010242220.2.
DR AlphaFoldDB; I1J2K8; -.
DR STRING; 15368.I1J2K8; -.
DR EnsemblPlants; KQJ84968; KQJ84968; BRADI_5g23970v3.
DR GeneID; 100833841; -.
DR Gramene; KQJ84968; KQJ84968; BRADI_5g23970v3.
DR KEGG; bdi:100833841; -.
DR eggNOG; KOG0804; Eukaryota.
DR HOGENOM; CLU_009969_1_0_1; -.
DR InParanoid; I1J2K8; -.
DR OMA; YIEHASD; -.
DR OrthoDB; 123540at2759; -.
DR Proteomes; UP000008810; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:EnsemblPlants.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0007265; P:Ras protein signal transduction; IBA:GO_Central.
DR GO; GO:0010029; P:regulation of seed germination; IEA:EnsemblPlants.
DR CDD; cd16457; RING-H2_BRAP2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR011422; BRAP2/ETP1_RRM.
DR InterPro; IPR047243; RING-H2_BRAP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR24007:SF10; BRAP2 RING ZNF UBP DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR Pfam; PF07576; BRAP2; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 234..274
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 271..364
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT REGION 23..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 403..467
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 60723 MW; A557DB3A8BDEA7D5 CRC64;
MFSLRIHSVE FPDAIADRTT AGADEVGTSS GAPGCITASS PISPRSGHPL PSTASPTTPL
ELPGATSAAS ARNPRIQHTR GILHLYRSST SSPASSYASA VAATPSSSSY SGPTAPQLPC
DSLLPSWRGT RLLVLAVPTR VSSDDFVRFC GPYVEHASDI RVISDDGVED RYSVLVEFED
QKSADGFYLD LNGWRFSSSE VEVCHVLFIV AVQYTSSAEI AVIPPVGSTE LPTCPVCIER
LDQDISGIVA TNCDHSFQCS CVSMWVSSSC PVCQFCQKLS ETPTDPTCSV CQTSENLWIC
VICGFVGCGR YKEGHAIRHW KGTQHCYSLD LETQRVWDYV GDSYVHRLNH SKSDVKHAKF
KSKCEYSGDN CVNCSCNDHS DMGGAIFSSK TETIVDEYNR VLASQLETQR EYYEALLSEA
KKEREQHISV AVDKAVNDKL QEMQLKLENL ALEKKKVAEM NEKLTKSQDI WRQTVKGIEE
RERAQLKLKD DTIIDLEEQI KDFKYNIKLQ KSIQKNAHAD DLQGGMLVPL AMESDSGKGK
RSSRTSRRRN
//
