ID I1LRC7_SOYBN Unreviewed; 683 AA.
AC I1LRC7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Nucleobase-ascorbate transporter 12 {ECO:0008006|Google:ProtNLM};
GN Name=100793041 {ECO:0000313|EnsemblPlants:KRH25169};
GN ORFNames=GLYMA_12G085600 {ECO:0000313|EMBL:KRH25169.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH25169.1};
RN [1] {ECO:0000313|EMBL:KRH25169.1, ECO:0000313|EnsemblPlants:KRH25169}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH25169};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH25169.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH25169}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH25169};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH25169.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH25169.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CM000845; KRH25169.1; -; Genomic_DNA.
DR EMBL; CM000845; KRH25170.1; -; Genomic_DNA.
DR RefSeq; XP_003539808.1; XM_003539760.3.
DR AlphaFoldDB; I1LRC7; -.
DR SMR; I1LRC7; -.
DR STRING; 3847.I1LRC7; -.
DR PaxDb; 3847-GLYMA12G09060-2; -.
DR EnsemblPlants; KRH25169; KRH25169; GLYMA_12G085600.
DR EnsemblPlants; KRH25170; KRH25170; GLYMA_12G085600.
DR GeneID; 100793041; -.
DR Gramene; KRH25169; KRH25169; GLYMA_12G085600.
DR Gramene; KRH25170; KRH25170; GLYMA_12G085600.
DR KEGG; gmx:100793041; -.
DR eggNOG; KOG1292; Eukaryota.
DR HOGENOM; CLU_017959_5_2_1; -.
DR InParanoid; I1LRC7; -.
DR OMA; WARRTGY; -.
DR OrthoDB; 345287at2759; -.
DR Proteomes; UP000008827; Chromosome 12.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF28; NUCLEOBASE-ASCORBATE TRANSPORTER 12; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 154..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 73897 MW; F558A069E95743D7 CRC64;
MSNSNPNNRN RHAPSPPEPK PMPPSSWAKK TGFRPKLSGE TNVTDSGPIT TPPPNVDLEA
GRVRTPATAN GVTNGDKAPV PVPPPPAAAK KRRDSDGVPK SSVLSTNGQA PAAEPPPRRT
ARHEEVVDGL PADDDEFVSR HSHMKYELRD SPGLVPIGVY GIQHYFSILG SLVLIPLVIV
PTMGGTHEET SMVVSTVLFV SGVTTLLHIA FGSRLPLIQG PSFVYLAPAL AIINSPEFQG
LNENKFKHIM RELQGAIIIG AAFQTLLGYT GLMSLLVRLI NPVVISPTIA AVGLSFYSYG
FPLVGTCIEI GAVQILVVIV FSLYLRKISV LGHRIFLIYA VPLGLAITWA FAFMLTEAGV
YSYKGCDANI PSSNMVSEHC RKHFSRMRHC RVDTSQALKS SSWFRFPYPL QWGTPVFHWK
MAIVMCVVSL ISSVDSVGSY HASSLLVASR PPTPGVLSRG IGLEGLASVL AGLWGTGTGS
TTLTENVHTI AVTKMGSRRA VQLGACFLIV LSLIGKVGGF IASIPEVMVA GLLCFMWAML
TALGLSNLRY SEAGSSRNII IVGLSLFFSL SIPAYFQQYG ISPNSNLSVP SYFQPYIVTS
HGPFHSKYGG LNYVLNTLFS LHMVIAFLVA FILDNTVPGS KQERGVYVWS EAEIARREPA
VANDYELPLK VGRIFRWVKW VGV
//
