ID I1M0S1_SOYBN Unreviewed; 752 AA.
AC I1M0S1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase {ECO:0000256|PIRNR:PIRNR037274};
DE EC=2.7.1.68 {ECO:0000256|PIRNR:PIRNR037274};
GN Name=100775866 {ECO:0000313|EnsemblPlants:KRH20721};
GN ORFNames=GLYMA_13G196700 {ECO:0000313|EMBL:KRH20721.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH20721.1};
RN [1] {ECO:0000313|EMBL:KRH20721.1, ECO:0000313|EnsemblPlants:KRH20721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH20721};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH20721.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH20721}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH20721};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH20721.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH20721.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-
CC phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-
CC inositol-4,5-bisphosphate) + ADP + H(+); Xref=Rhea:RHEA:14425,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58178,
CC ChEBI:CHEBI:58456, ChEBI:CHEBI:456216; EC=2.7.1.68;
CC Evidence={ECO:0000256|PIRNR:PIRNR037274};
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DR EMBL; CM000846; KRH20721.1; -; Genomic_DNA.
DR RefSeq; XP_003542821.1; XM_003542773.3.
DR AlphaFoldDB; I1M0S1; -.
DR SMR; I1M0S1; -.
DR STRING; 3847.I1M0S1; -.
DR PaxDb; 3847-GLYMA13G26670-1; -.
DR EnsemblPlants; KRH20721; KRH20721; GLYMA_13G196700.
DR GeneID; 100775866; -.
DR Gramene; KRH20721; KRH20721; GLYMA_13G196700.
DR KEGG; gmx:100775866; -.
DR eggNOG; KOG0229; Eukaryota.
DR HOGENOM; CLU_004312_6_4_1; -.
DR InParanoid; I1M0S1; -.
DR OMA; FYIGEWC; -.
DR OrthoDB; 340426at2759; -.
DR Proteomes; UP000008827; Chromosome 13.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd17302; PIPKc_AtPIP5K_like; 1.
DR Gene3D; 3.30.810.10; 2-Layer Sandwich; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 4.
DR Gene3D; 3.30.800.10; Phosphatidylinositol Phosphate Kinase II Beta; 1.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR017163; PIno-4-P-5_kinase_pln.
DR InterPro; IPR027483; PInositol-4-P-4/5-kinase_C_sf.
DR InterPro; IPR002498; PInositol-4-P-4/5-kinase_core.
DR InterPro; IPR027484; PInositol-4-P-5-kinase_N.
DR InterPro; IPR023610; PInositol-4/5-P-5/4-kinase.
DR PANTHER; PTHR23086:SF113; PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE 6; 1.
DR PANTHER; PTHR23086; PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE; 1.
DR Pfam; PF02493; MORN; 7.
DR Pfam; PF01504; PIP5K; 1.
DR PIRSF; PIRSF037274; PIP5K_plant_prd; 2.
DR SMART; SM00698; MORN; 7.
DR SMART; SM00330; PIPKc; 1.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR SUPFAM; SSF56104; SAICAR synthase-like; 1.
DR PROSITE; PS51455; PIPK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRNR:PIRNR037274, ECO:0000256|PROSITE-
KW ProRule:PRU00781};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|PIRNR:PIRNR037274};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR037274, ECO:0000256|PROSITE-
KW ProRule:PRU00781}; Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR037274}.
FT DOMAIN 353..749
FT /note="PIPK"
FT /evidence="ECO:0000259|PROSITE:PS51455"
FT REGION 295..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 85284 MW; 4164CAD86E5B201E CRC64;
MNKELTSFVK AWEAAVRKSA GPKRRANSIF TPMSVAHVDD DDDATRNVVG EVEKILPNGD
FYTGQWLDNN GPHGQGKYLW TDGCMYVGEW QKGGIMGKGR FSWPSGATYE GDFKGGYMDG
KGTFIGSSGD TYKGCWVMEL RHGQGTQSYP NGDFYDGEWR KGLQNGHGRY QWKNGNHYIG
QWRNGLFHGN GTMMWSNGNR YDGCWEEGLP KGNGTFRWGG DGSFYVGVWS KDPKEQNGTY
YPSGSCAGHL EWDPQELFSL DLVECSVCGL EKVAIYPSHK SLNMLEGDNK MCKKGTDGTG
RTRRMSVDAR ISNYSSEDGS YSSYNGSRSS QVDNSIPRVP HLRLKAPKRQ GETISQGHKN
YELMLNLQLG IRHAVGRPAP STSLDLKSSA FDPKEKVWTK FPPEGSKHTP PHQSCEFRWK
DYCPVVFRAL RKLFKVDPAD YMLSLCGNDA LRELSSPGKS GSFFYLTNDD RYMIKTMKKS
EVKVFLRMLP GYYKHVRAFE NTLVTKFFGL HCVKLTGTAQ KKVRFVIMGN LFCSQYPIHR
RFDLKGSTFG RTTDKPESEI EPTTTLKDLD LNYIFRLRKS WFQEFCRQVD RDCDFLEHER
IMDYSMLVGL HFRGMSCGDN VTPSGHSPGP QTPTGHGNFD DGAPRLSGVD VDHLVVDPNR
WIQLGISMPA RAEMTVRKSC DTPQLVGEPT GELYEIIIFF GIIDILQDYD ISKKLEHAYK
SFQYDPTSIS AVDPRLYSKR FRDFIFRVFV ED
//
