ID I1M8X6_SOYBN Unreviewed; 750 AA.
AC I1M8X6;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=CSC1-like protein RXW8 {ECO:0008006|Google:ProtNLM};
GN Name=100814561 {ECO:0000313|EnsemblPlants:KRH15477};
GN ORFNames=GLYMA_14G090700 {ECO:0000313|EMBL:KRH15477.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH15477};
RN [1] {ECO:0000313|EMBL:KRH15477.1, ECO:0000313|EnsemblPlants:KRH15477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH15477};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH15477.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH15477}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH15477};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH15477.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH15477.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; CM000847; KRH15477.1; -; Genomic_DNA.
DR RefSeq; XP_003545361.2; XM_003545313.3.
DR AlphaFoldDB; I1M8X6; -.
DR SMR; I1M8X6; -.
DR PaxDb; 3847-GLYMA14G10320-1; -.
DR EnsemblPlants; KRH15477; KRH15477; GLYMA_14G090700.
DR GeneID; 100814561; -.
DR Gramene; KRH15477; KRH15477; GLYMA_14G090700.
DR KEGG; gmx:100814561; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002458_7_2_1; -.
DR InParanoid; I1M8X6; -.
DR OMA; QIIYKVG; -.
DR OrthoDB; 1753647at2759; -.
DR Proteomes; UP000008827; Chromosome 14.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IBA:GO_Central.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 595..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 185..340
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 351..618
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 699..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 84704 MW; 65D133F0E3BF76EE CRC64;
MDIAALLTSA GINIAVCVVL FSFYSVLRKQ PSNVNVYFGR RLASQHSRRI DLCLERFVPS
PSWILKAWET SEDEILAIGG LDAVVFVRIL VFSIQVFSIA AAICTVMVLP VNYNGMGGMR
KNIPFESLEV FTIENVKEGS KWLWVHCLAL YIITLSACAL LYFEYKSITN LRLLHIIGSP
PNPSHFTILV RSIPWSSEES YCETVKKFFS YYHASTYLSH QMIYKSGKVQ KLKDDAEHIC
KVIRDASLEK TCKPSFTKCC CYGAPTFSFK KISTETGSTH GRTCNNDLHL DTGKKECPAA
FVFFKSRYAA LTAAQVLQTS NPMLWVTDVA PEPHDVYWSN ICIPYRQLWI RKIATLVASV
AFMLVFLIPV TFVQGLTQLD KLQKMFPFLT GILKEKFVNQ VVTGYLPSVI LVLFLCAVPP
VMILLSSVEG SISRSERKKS ACFKVLYFTI WNVFFVNVFT GSVISQLLVF SSVTDLPAQL
AKAVPLQATF FTTYILSSGW ASLAVEVMQI FPLLCNLFQR FILRLKEDAL DGSLSFPYHT
EVPRILLFGF LGFTCAILAP LMLPFLLIYF FIAYLVYRNQ IINVYITKYD SGGQYWPIVH
NTTVFSLLFS QLIALGVFGL KRSSVTSGFT IPLLIGTLLF HQYCRQRFLP VFRNNSAQIL
IDLDRRDEHC GRVEEIYEHL CSAYNQSSLM PHSTSQAKCV SLHEDKDSSP SSSEDMEKGN
EKEINQKDRP RPVQRSLSLS SDKSVLGVKQ
//
